ArticleNature2022
A human brain vascular atlas reveals diverse mediators of Alzheimer's risk.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 559 papers, 3 of them syntheses that pooled it.
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559citing papers in PubMed, 3 pooled it
–field-weighted citation impact
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
559 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Endovascular biopsy in neurointerventional surgery: A systematic review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Pooled it
- Improving reproducibility of differentially expressed genes in single-cell transcriptomic studies of neurodegenerative diseases through meta-analysis.Nature communications · 2025Pooled it
- Dissecting the Genetic Architecture of Intracranial Aneurysms.Circulation. Genomic and precision medicine · 2025Pooled it
- Patient-derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones.Brain pathology (Zurich, Switzerland) · 2026Article
- Molecular Pathogenesis of Cerebral Amyloid Angiopathy in Alzheimer's Disease: The Role of the Central Fibrinolytic Cascade at the Neurovascular Unit.Molecular neurobiology · 2026Review
- Vascular profiling of the spinal cord and cortex reveals region-specific endothelial dysfunction and fibroblast remodeling in human ALS.Acta neuropathologica communications · 2026Article
- Bisphenol A Exposure Perturbs the Immune Microenvironment in Alzheimer's Disease: Insights from Network Toxicology and Single-Cell Transcriptomics.Journal of molecular neuroscience : MN · 2026Article
- MAFG as a Redox-Sensitive Node Linking Peripheral Immune Reprogramming to Cognitive Risk in the Sepsis-to-Alzheimer's Disease Continuum: Single-Cell Dissection and Adoptive-Transfer Validation.CNS neuroscience & therapeutics · 2026Article
- Microglial states revisited: from homeostasis to disease.Nature reviews. Neuroscience · 2026Review
- Differentiation of arterioles and capillaries in human blood vessel organoids with decellularized splenic matrix.Bioactive materials · 2026Article
- Article
- ABCC9/SUR2 has a Complex Expression Pattern in Human Brain Gliovascular Unit Cells, Including Astrocytes.Journal of molecular neuroscience : MN · 2026Article
- Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis.Cell · 2026Article
- Article
- Plasma neuroimmune pathway signatures are associated with clinical impairment and lower MRI-derived hippocampal volume across the Alzheimer's disease continuum.European geriatric medicine · 2026Article
- Cell-to-Cell Signaling Networks at the Blood-Brain Barrier in Health and Disease.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- VINE-seq and MultiVINE-seq for single-nucleus and multiome profiling of the brain vasculature.Nature protocols · 2026Review
- Cellular and signalling mechanisms that regulate the blood-brain barrier.Nature reviews. Molecular cell biology · 2026Review
- Article
- Robust Inference With Ghostknockoffs in Genome-Wide Association Studies With Sample Relatedness.Genetic epidemiology · 2026Article
499 more citing papers are in PubMed but not listed here.
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Authors and funding
24 authors.
Andrew C YangDepartment of Anatomy, University of California San Francisco, San Francisco, CA, USA. andrew.yang@ucsf.edu.ORCID http://orcid.org/0000-0002-6756-4746
Ryan T Vest *Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Fabian Kern *Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-8223-3750
Davis P LeeDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Maayan AgamDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Christina A MaatDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Patricia M LosadaDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Michelle B ChenDepartment of Anatomy, University of California San Francisco, San Francisco, CA, USA.
Nicholas SchaumDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Nathalie KhouryDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Angus TolandDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Kruti CalcuttawalaDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Heather ShinDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Róbert PálovicsDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Andrew ShinDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Elizabeth Y WangDepartment of Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jian LuoVeterans Administration Palo Alto Healthcare System, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0002-2064-8467
David GateDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0481-9657
Walter J Schulz-SchaefferInstitute for Neuropathology, Saarland University Hospital and Medical Faculty of Saarland University, Homburg, Germany.ORCID http://orcid.org/0000-0001-5886-2322
Pauline ChuChair for Clinical Bioinformatics, Saarland University, Saarbrücken, Germany.
Julie A SiegenthalerDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
M Windy McNerneyDepartment of Psychiatry, Stanford University School of Medicine, Stanford, CA, USA.
Andreas KellerDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-5361-0895
Tony Wyss-CorayBakar Aging Research Institute, University of California San Francisco, San Francisco, CA, USA. twc@stanford.edu.ORCID http://orcid.org/0000-0001-5893-0831
Funding
Stanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2020 to 2026
$29.0MStanford Training Program in Aging ResearchT32AG047126 · NIA · STANFORD UNIVERSITY · PI VYJEYANTHI S PERIYAKOIL, TONY WYSS-CORAY · 2014 to 2026
$4.3MTargeting Cerebrovascular TGF Signaling in Alzheimer's DiseaseRF1AG059694 · NIA · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI LUO, JIAN, WYSS-CORAY, TONY · 2018 to 2018
$3.0MAmerican Heart Association-American Stroke AssociationNIA NIH HHS P30 AG066515NIA NIH HHS RF1 AG059694NIA NIH HHS T32 AG047126NIH HHS 1RF1 AG059694NIH HHS T32 AG0047126
Abstract
The human brain vasculature is of great medical importance: its dysfunction causes disability and death
Indexed as
Alzheimer DiseaseBrainDisease SusceptibilityAnimalsCerebral CortexGenome-Wide Association StudyHippocampusHumansMiceMicrogliaPericytesTranscriptome
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.