Evidence map›Paper›PMID 35165346›Full record

ArticleScientific reports2022

Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles.

Rabaa Algotiml, Ali Gab-Alla, Roshdi Seoudi, Hussein H Abulreesh, Mahmoud Zaki El-Readi, Khaled Elbanna

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Silver-LoadedMarine drugs · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Tackling carbapenem-resistantBiotechnology notes (Amsterdam, Netherlands) · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rabaa AlgotimlDepartment of Biology, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Ali Gab-AllaDepartment of Biology, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Roshdi SeoudiSpectroscopy Department, Physics Division, National Research Center, Dokki, Cairo, 12622, Egypt.
Hussein H AbulreeshDepartment of Biology, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Mahmoud Zaki El-ReadiDepartment of Clinical Biochemistry, Faculty of Medicine, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Khaled ElbannaDepartment of Biology, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia. kab00@fayoum.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosynthesis of silver nanoparticles (AgNPs) is emerging as a simple and eco-friendly alternative to conventional chemical synthesis methods. The role of AgNPs is expanding as antimicrobial and anticancer agents, sensors, nanoelectronic devices, and imaging contrast agents. In this study, biogenic AgNPs were synthesized using extracts of different marine algae species, including Ulva rigida (green alga), Cystoseira myrica (brown alga), and Gracilaria foliifera (red alga), as reducing and capping agents. The Physiochemical properties, cytotoxicity, anticancer and antimicrobial activities of the biosynthesized AgNPs were assessed. Surface plasmonic bands of the biosynthesized AgNPs capped with U. rigida, C. myrica, and G. foliifera extracts were visually observed to determine a colour change, and their peaks were observed at 424 nm, 409 nm, and 415 nm, respectively, by UV-Vis spectroscopy; transmission electron microscopy (TEM) indicated an almost spherical shape of AgNPs with nanoscale sizes of 12 nm, 17 nm, and 24 nm, respectively. Fourier transform-infrared (FTIR) spectroscopy analysis suggested that different molecules attached to AgNPs through OH, C=O, and amide groups. The major constituents of the aqueous algal extracts included, terpenoids, polyphenols, sulfonates, polysaccharides, fatty acids, chlorophylls, amide proteins, flavonoids, carotenoids, aliphatic fluoro compounds, volatile compounds, alkalines, pyruvic acid and agar groups. The cytotoxicity and anticancer activities of the biosynthesized AgNPs were assessed using Artemia salina nauplii, normal skin cell lines (HFb-4), and breast cancer cell lines (MCF-7 cell line). The lethality was found to be directly proportional to the AgNP concentration. The IC

Indexed as

AnimalsAnti-Infective AgentsAntineoplastic AgentsArtemiaChlorophytaFungiHumansMCF-7 CellsMetal NanoparticlesPhaeophyceaePlant ExtractsRhodophytaSilverSpectroscopy, Fourier Transform InfraredAnti-Infective AgentsAntineoplastic AgentsPlant ExtractsSilver

Identifiers

PMID35165346
PMCPMC8844081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.