ArticleScientific reports2022
Plasmid-mediated colistin resistance and ESBL production in Escherichia coli from clinically healthy and sick pigs.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Co-occurrence of plasmid-mediated colistin resistance gene, mcr-1 and blaScientific reports · 2026Article
- Phenotypic and Genomic Analysis of Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2026Article
- mcr gene family evolution and structural mechanisms of colistin resistance: from mcr-1 to emerging variants.Archives of microbiology · 2026Review
- Seasonal prevalence of extended-spectrum β-lactamase-producing bacteria in food-chain animals, humans, and the surrounding environment in Fayoum governorate: a one health approach.Frontiers in microbiology · 2026Article
- Fecal carriage, transferable β-lactam resistance, and efflux pump contribution in third-generation cephalosporin-resistantVeterinary world · 2026Article
- Antimicrobial resistance, extended-spectrum β-lactamase determinants, and virulence gene profiles ofVeterinary world · 2026Article
- Trends in Colistin Resistance and Multidrug-Resistant Phenotypes Among Gram-Negative Bacilli: A Retrospective Analysis.Molecules (Basel, Switzerland) · 2025Article
- Antibiotic Resistance in the Philippines: Environmental Reservoirs, Spillovers, and One-Health Research Gaps.Frontiers in microbiology · 2025Review
- Detection and Characterisation of Colistin-ResistantMicroorganisms · 2024Article
- Characteristics of the extended-spectrum-β-lactamase-producing Escherichia coli isolated from diseased livestock and poultry in Taiwan.Scientific reports · 2024Article
- PmrB Y358N, E123D amino acid substitutions are not associated with colistin resistance but with phylogeny inMicrobiology spectrum · 2024Article
- The Global Rise of ESBL-ProducingAnimals : an open access journal from MDPI · 2024Review
- Phenotypic and molecular characterization of multidrug-resistant Enterobacterales isolated from clinical samples in Palestine: a focus on extended-spectrum β-lactamase- and carbapenemase-producing isolates.BMC infectious diseases · 2024Article
- Article
- Improving phage therapy by evasion of phage resistance mechanisms.JAC-antimicrobial resistance · 2024Review
- Metagenomic insights into isolable bacterial communities and antimicrobial resistance in airborne dust from pig farms.Frontiers in veterinary science · 2024Article
- Extended-Spectrum β-Lactamases (ESBL) Producing Bacteria in Animals.Antibiotics (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to determine the percentage of colistin resistant and ESBL-producing Escherichia coli from clinically sick and healthy pigs and understand the molecular mechanisms underlying colistin resistance and ESBL production. A total of 454 E. coli isolates from healthy pigs (n = 354; piglets, n = 83; fattening pigs, n = 142 and sows, n = 100) and sick pigs (n = 100) were examined for antimicrobial susceptibility, chromosomal and plasmid-mediated colistin resistance mechanisms and ESBL genes. The healthy (41%) and sick pig (73%) isolates were commonly resistant to colistin. Three mcr genes including mcr-1 (10.4%), mcr-2 (1.1%) and mcr-3 (45%) were detected, of which mcr-3 was most frequently detected in the healthy (33%) and sick pig (57%) isolates. Coexistence of mcr-1/mcr-3 and mcr-2/mcr-3 was observed in piglets (23%), fattening pig (3.5%) and sick pig (13%) isolates. Three amino acid substitutions including E106A and G144S in PmrA and V161G in PmrB were observed only in colistin-resistant isolates carrying mcr-3. The percentage of ESBL-producing E. coli was significantly higher in the sick pigs (44%) than the healthy pigs (19.2%) (P = 0.00). The bla
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