ArticleScientific reports2022
The effects of the COVID-19 pandemic on neuropsychiatric symptoms in dementia and carer mental health: an international multicentre study.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- The Global Impact of COVID-19 Control Measures on People With Dementia Living at Home and Their Carers: A Systematic Review of Quantitative and Qualitative Research Across 27 Countries.Brain and behavior · 2025Pooled it
- Technological interventions in European dementia care: a systematic review of acceptance and attitudes among people living with dementia, caregivers, and healthcare workers.Frontiers in neurology · 2024Pooled it
- The impact of the COVID-19 pandemic on mortality in people with dementia without COVID-19: a systematic review and meta-analysis.BMC geriatrics · 2022Pooled it
- The DREAMS START intervention for sleep in dementia: Long-term follow-up of a randomized controlled trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Trial
- Mobile Health Interventions to Support Patients With Dementia During the COVID-19 Pandemic: A Systematic Review.Health science reports · 2026Review
- Microbiota and Alzheimer's disease: mechanistic insights from a multi-organ perspective.Translational neurodegeneration · 2026Review
- Family physician and specialist care for persons with dementia living in the community: through thick and thin.Family practice · 2025Article
- Updates and future perspectives on neuropsychiatric symptoms in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Apathy in Neuropsychiatric Disorders: Clinical Characteristics, Neurobiological Mechanisms, and Therapeutic Strategies.Behavioural neurology · 2025Review
- MRI detects blood-brain barrier alterations in a rat model of Alzheimer's disease and lung infection.Npj imaging · 2025Article
- Risk factors for severe COVID-19 outcomes in the Asia-Pacific region: a literature review.Frontiers in public health · 2025Review
- Lessons learned for pandemic preparedness in the neurodegenerative research and clinical fields: an advice report based on Parkinson's disease as an example.BMC neurology · 2024Article
- Mental Health Impacts of COVID-19: Does Prepandemic Cognition and Dementia Status Matter?The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- What influences life expectancy in people with dementia? Social support as an emerging protective factor.Age and ageing · 2024Article
- Review
- The Impact of the COVID-19 Pandemic on the Severity of Alcohol Use Disorder: Significance of Dual Disorders.International journal of environmental research and public health · 2023Article
- Frontotemporal lobar degeneration.Nature reviews. Disease primers · 2023Review
- Risk factors for post-COVID cognitive dysfunctions: the impact of psychosocial vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- An Update on Apathy in Alzheimer's Disease.Geriatrics (Basel, Switzerland) · 2023Review
- The clinical course and outcomes of SARS-CoV-2 virus infection in children: a 24-week follow-up study in Sulaimaniyah, Iraq.BMC pediatrics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
Abstract
As a global health emergency, the rapid spread of the novel coronavirus disease (COVID-19) led to the implementation of widespread restrictions (e.g., quarantine, physical/social distancing measures). However, while these restrictions reduce the viral spread of COVID-19, they may exacerbate behavioural and cognitive symptoms in dementia patients and increase pressure on caregiving. Here, we aimed to assess the impact of COVID-19 and related restrictions on both carers and people living with dementia across the world. We conducted an international survey (Australia, Germany, Spain, and the Netherlands) to assess the impact of COVID-19 on carers and people living with dementia. People with dementia experienced worsened neuropsychiatric symptoms since the outbreak of COVID-19, most commonly, depression, apathy, delusions, anxiety, irritability, and agitation. Regression analyses revealed that limited understanding of the COVID-19 situation and not living with the carer was associated with worsened neuropsychiatric symptoms. Carers also reported a decline in their own mental health, increased stress and reduced social networks as a result of COVID-19 and related restrictions. Regression analyses revealed uncertainty about the future and loneliness were associated with worsened carer mental health. Findings from this study will inform strategies for the development of support services and compassionate protocols that meet the evolving needs of those living with dementia and their carers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.