Evidence map›Paper›PMID 35165228›Full record

ArticleJournal of addiction medicine

Initiating Long-acting Injectable Naltrexone: Procedure for a Second Attempt After a First Attempt Fails.

Matisyahu Shulman, Mei Chen Hu, Edward V Nunes, Adam Bisaga

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matisyahu ShulmanFrom the Department of Psychiatry, Division on Substance Use Disorders, New York State Psychiatric Institute and Columbia University Irving Medical Center, New York, NY (MS, EVN, AB), Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY (MS, MC, EVN, AB).
Mei Chen Hu
Edward V Nunes
Adam Bisaga
Columbia University · US

Funding

Improved Strategies for Outpatient Opioid DetoxificationR01DA030484 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI BISAGA, ADAM · 2011 to 2015
$3.1M
NIDA NIH HHS R01 DA030484
6 · The paper itself

Abstract

BACKGROUND AND

objectiveMany patients are unable to initiate long-acting injectable naltrexone (XR-NTX) on a first attempt, due to the prerequisite abstinence and withdrawal from opioids.

methodsThirty patients who were unable to initiate XR-NTX were recruited to receive buprenorphine for 1 week, followed by a 3-week buprenorphine taper, and an ascending titration of oral naltrexone before XR-NTX injection.

resultsEight (27%) initiated XR-NTX, 7 (23%) transitioned to buprenorphine maintenance treatment and 15 (50%) were lost to follow up. CONCLUSION AND SCIENTIFIC SIGNIFICANCE: A second attempt at XR- NTX initiation using buprenorphine stabilization and cross taper may be a reasonable approach for some patients.

Indexed as

BuprenorphineOpioid-Related DisordersAnalgesics, OpioidDelayed-Action PreparationsHumansInjections, IntramuscularNaltrexoneNarcotic AntagonistsAnalgesics, OpioidBuprenorphineDelayed-Action PreparationsNaltrexoneNarcotic Antagonists

Identifiers

PMID35165228
PMCPMC9375774
OpenAlexW4212868735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.