Evidence map›Paper›PMID 35165190›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

MadR mediates acyl CoA-dependent regulation of mycolic acid desaturation in mycobacteria.

Charlotte Cooper, Eliza J R Peterson, Rebeca Bailo, Min Pan, Albel Singh, Patrick Moynihan, Makoto Nakaya, Nagatoshi Fujiwara, Nitin Baliga, Apoorva Bhatt

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Charlotte CooperSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0003-4855-4187
Eliza J R PetersonInstitute for Systems Biology, Seattle, WA 98109.ORCID 0000-0003-2934-5267
Rebeca BailoSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0003-3580-1273
Min PanInstitute for Systems Biology, Seattle, WA 98109.ORCID 0000-0002-9781-0637
Albel SinghSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Patrick MoynihanSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0003-4182-6223
Makoto NakayaOtemae College of Nutrition, Osaka 599-8531, Japan.ORCID 0000-0002-5890-2272
Nagatoshi FujiwaraDepartment of Food and Nutrition, Faculty of Contemporary Human Life Science, Tezukayama University, Nara 631-8585, Japan.ORCID 0000-0001-5566-681X
Nitin BaligaInstitute for Systems Biology, Seattle, WA 98109; nitin.baliga@isbscience.org a.bhatt@bham.ac.uk.ORCID 0000-0001-9157-5974
Apoorva BhattSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK; nitin.baliga@isbscience.org a.bhatt@bham.ac.uk.ORCID 0000-0002-6655-1636
University of Birmingham · GBInstitute for Systems Biology · USLawrence Berkeley National Laboratory · USOtemae College of Nutrition · JPTezukayama University · JP

Funding

Technology CoreU19AI135976 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI ADEREM, ALAN A · 2018 to 2022
$17.0M
A systems analysis of drug tolerance in Mycobacterium tuberculosisR01AI128215 · NIAID · INSTITUTE FOR SYSTEMS BIOLOGY · PI Nitin S Baliga · 2017 to 2026
$8.8M
Site Specific Immunophenotyping Assays of COVID19 Patients to Align with NIAID National StudyR01AI141953 · NIAID · INSTITUTE FOR SYSTEMS BIOLOGY · PI BALIGA, NITIN S · 2019 to 2023
$5.7M
Medical Research Council G0600105NIAID NIH HHS R01 AI128215NIAID NIH HHS R01 AI141953NIAID NIH HHS U19 AI135976
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acyl Coenzyme ABacterial ProteinsCell WallFatty Acid DesaturasesFatty AcidsLipid MetabolismMycobacteriumMycobacterium InfectionsMycobacterium tuberculosisMycolic AcidsRacemases and EpimerasesTranscription FactorsAcyl Coenzyme ABacterial ProteinsFatty Acid DesaturasesFatty AcidsMadR1 protein, Mycobacterium tuberculosisMycolic AcidsRacemases and EpimerasesTranscription Factorscell envelopeMycobacteriummycolic acidTetR regulatortuberculosis

Identifiers

PMID35165190
PMCPMC8872791
OpenAlexW4213250219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.