Evidence map›Paper›PMID 35165127›Full record

ArticleBMJ case reports2022

Challenges in the management of extensive aplasia cutis congenita.

Alvin Ngeow, Cheryl Hui, Alvin Wen Choong Chua, Mark Koh, Yee Siang Ong, Woei Bing Poon

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alvin NgeowDepartment of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore alvin.ngeow.j.h@singhealth.com.sg.ORCID http://orcid.org/0000-0002-1767-4402
Cheryl HuiPlastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore.
Alvin Wen Choong ChuaSkin Bank Unit, Singapore General Hospital, Singapore.
Mark KohDepartment of Dermatology, KK Women's and Children's Hospital, Singapore.ORCID http://orcid.org/0000-0002-4136-4105
Yee Siang OngPlastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore.
Woei Bing PoonDepartment of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore.
Singapore General Hospital · SGKK Women's and Children's Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aplasia cutis congenita (ACC) is a rare group of congenital disorders characterised by focal or widespread absence of skin, predominantly affecting the scalp. A Malay female infant was born at 37 weeks with extensive ACC, affecting 37% of total body surface area, including her scalp and trunk. There is no consensus on the management of ACC given the rarity and variable presentation. A multi-disciplinary team comprising neonatologists, paediatric dermatologists, plastic surgeons and medical laboratory scientists at the skin bank, employed a more aggressive surgical approach with the aim of avoiding potentially catastrophic morbidity, including sagittal sinus haemorrhage and brain herniation. Out of several surgical options, the team used a staged artificial dermal matrix (Integra) and cultured epithelial autograft application, followed by regular wound dressing, and eventually allowed the child to achieve complete epithelialisation of her trunk, and most of scalp before she was discharged from hospital.

Indexed as

Ectodermal DysplasiaBandagesChildFemaleHemorrhageHumansInfantScalpSkindermatologyneonatal and paediatric intensive careplastic and reconstructive surgery

Identifiers

PMID35165127
PMCPMC8845208
OpenAlexW4213217999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.