Evidence map›Paper›PMID 35165110›Full record

ArticleBMJ open2022

Investigating the effect of macro-scale estimators on worldwide COVID-19 occurrence and mortality through regression analysis using online country-based data sources.

Sabri Erdem, Fulya Ipek, Aybars Bars, Volkan Genç, Esra Erpek, Shabnam Mohammadi, Anıl Altınata, Servet Akar

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04486508 (Intermediate-dose Versus Standard Prophylactic Anticoagulation In cRitically-ill pATIents With COVID-19), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04486508 phase3completednot on this map

Intermediate-dose Versus Standard Prophylactic Anticoagulation In cRitically-ill pATIents With COVID-19: An opeN Label Randomized Controlled Trial---A Randomized Trial of Atorvastatin vs. Placebo In Critically-ill Patients With COVID-19

TypeinterventionalSponsorRajaie Cardiovascular Medical and Research CenterRan2020 to 2021Enrolled600ConditionsCovid19Armsintermediate dose Enoxaparin/ unfractionated heparin, standard prophylactic dose Enoxaparin/ unfractionated heparin, Atorvastatin 20mg, Matched placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sabri ErdemDepartment of Business Administration, Dokuz Eylül University, Izmir, Turkey.
Fulya IpekFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey fulya.ipek@hacettepe.edu.tr.ORCID 0000-0001-7606-042X
Aybars BarsSocial Sciences Institute, Dokuz Eylül University, Izmir, Turkey.
Volkan GençSocial Sciences Institute, Dokuz Eylül University, Izmir, Turkey.
Esra ErpekDepartment of Internal Medicine, Division of Rheumatology Atatürk Education and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey.
Shabnam MohammadiSocial Sciences Institute, Dokuz Eylül University, Izmir, Turkey.
Anıl AltınataSocial Sciences Institute, Dokuz Eylül University, Izmir, Turkey.
Servet AkarDepartment of Internal Medicine, Division of Rheumatology Atatürk Education and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate macro-scale estimators of the variations in COVID-19 cases and deaths among countries.

designEpidemiological study.

settingCountry-based data from publicly available online databases of international organisations.

participantsThe study involved 170 countries/territories, each of which had complete COVID-19 and tuberculosis data, as well as specific health-related estimators (obesity, hypertension, diabetes and hypercholesterolaemia). PRIMARY AND SECONDARY OUTCOME MEASURES: The worldwide heterogeneity of the total number of COVID-19 cases and deaths per million on 31 December 2020 was analysed by 17 macro-scale estimators around the health-related, socioeconomic, climatic and political factors. In 139 of 170 nations, the best subsets regression was used to investigate all potential models of COVID-19 variations among countries. A multiple linear regression analysis was conducted to explore the predictive capacity of these variables. The same analysis was applied to the number of deaths per hundred thousand due to tuberculosis, a quite different infectious disease, to validate and control the differences with the proposed models for COVID-19.

resultsIn the model for the COVID-19 cases (R

conclusionsThis study recommends the new predictors explaining the global variability of COVID-19. Thus, it might assist policymakers in developing health policies and social strategies to deal with COVID-19. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov Registry (NCT04486508).

Indexed as

COVID-19Health PolicyHumansInformation Storage and RetrievalRegression AnalysisSARS-CoV-2COVID-19health policypublic health

Identifiers

PMID35165110
PMCPMC8844970

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.