ReviewPerioperative medicine (London, England)2022
Postoperative decrease of albumin (ΔAlb) as early predictor of complications after gastrointestinal surgery: a systematic review.
Review in Perioperative medicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- The impact of sarcopenia on esophagectomy for cancer: a systematic review and meta-analysis.BMC surgery · 2023Pooled it
- Short-term home-based multimodal prehabilitation for perioperative functional recovery in prefrail and frail older men undergoing radical prostatectomy: a randomized controlled trial.BMC geriatrics · 2026Trial
- Role of Oral Nutritional Supplements in Minimizing the Risk of Postoperative Malnutrition in Patients Undergoing Gastrointestinal Surgery.Journal of clinical medicine · 2026Article
- Albumin 20% in surgical and critically ill patients; a comprehensive review.Critical care (London, England) · 2026Review
- Observational
- Perioperative nutritional support is associated with attenuated early postoperative albumin decline after gastrectomy for gastric cancer: a retrospective cohort study and machine learning prediction model.Frontiers in medicine · 2026Article
- Preoperative and early postoperative albumin thresholds, rather than ΔAlb, predict severe complications after colorectal cancer surgery: a multifactorial model and nomogram.Frontiers in oncology · 2026Article
- A retrospective case-control study of Da Vinci robotic versus laparoscopic radical gastrectomy for gastric cancer under an enhanced recovery after surgery protocol.Frontiers in oncology · 2026Article
- Association between postoperative nutritional status and time to initiation of adjuvant chemotherapy in gastrointestinal cancers: a restricted cubic spline analysis.Frontiers in nutrition · 2026Article
- Global burden of paralytic ileus and intestinal obstruction in young and middle-aged adults (15-49 years): a systematic analysis from global burden of disease study 2021.European journal of medical research · 2025Article
- Article
- Article
- Prognostic value of postoperative decrease of albumin (ΔAlb) in combination with GLIM-defined malnutrition for the prediction of postoperative outcomes in rectal cancer patients with normal preoperative albumin levels.Frontiers in nutrition · 2025Article
- Postoperative decrease in serum albumin as predictor of early acute periprosthetic infection after total knee arthroplasty.Journal of orthopaedic surgery and research · 2024Article
- Article
- Assessing the perioperative gain of weight (Δweight) as a determinant of morbidity after kidney transplantation: a retrospective exploratory study.Scientific reports · 2024Article
- Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study.BMC musculoskeletal disorders · 2024Article
- Article
- Serum concentrations of proinflammatory biomarker interleukin-6 (IL-6) as a predictor of postoperative complications after elective colorectal surgery.World journal of surgical oncology · 2023Article
- Assessment of the Predictive Value of Preoperative Serum Albumin and Postoperative Albumin Drop (ΔAlb) for Complications after Pancreas Surgery: A Single-Center Cross-Sectional Study.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative complications are frequent after gastrointestinal surgery and early prediction remains an unmet need. Serum albumin shows a rapid decrease after surgery, and this decline (ΔAlb) may reflect the intensity of the surgical stress response and thereby be a predictor of postoperative complications. This study aimed to comprehensively review the available data on ΔAlb in gastrointestinal surgery.
methodsPRISMA guidelines were followed to conduct a systematic review of the literature in MEDLINE and Embase. Studies assessing the role of ΔAlb to predict complications after gastrointestinal surgery were included.
resultsA total of 1256 articles were screened, and 16 studies were included in the final analysis: 7 prospective and 9 retrospective trials. Sensitivity of ΔAlb to predict postoperative complications ranged from 63 to 84%, whereas specificity ranged from 61 to 86%. Nine out of the 16 included studies established a threshold of ΔAlb to predict morbidity (range: 5-11 g/l or 14-27%).
conclusionΔAlb appeared as a valuable and promising biomarker to anticipate complications after gastrointestinal surgery. Future efforts are needed to determine whether and how ΔAlb may be integrated in clinical practice to guide clinicians in the perioperative management of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.