Evidence map›Paper›PMID 35164828›Full record

ArticleBMC research notes2022

The type of anticoagulant used for plasma collection affects in vitro Rhodococcus equi assays.

Alejandra A Rivolta, Dana C Pittman, Amanda J Kappes, Robert K Stancil, Clark Kogan, Macarena G Sanz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alejandra A RivoltaDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.
Dana C PittmanDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.
Amanda J KappesDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA.
Robert K StancilDepartment of Mathematics, Washington State University, Pullman, WA, USA.
Clark KoganDepartment of Mathematics, Washington State University, Pullman, WA, USA.
Macarena G SanzDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA. macarena@wsu.edu.ORCID http://orcid.org/0000-0001-6565-9947
Washington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe efficacy of Rhodococcus equi-specific hyperimmune plasma (HIP) is usually evaluated in vitro. Anticoagulants (AC) used for plasma collection can negatively impact bacterial replication but their effect on R. equi growth has not been evaluated. The aim of this study was to establish the effect that AC routinely used in veterinary medicine (ACD, K

resultsThere was no direct effect of ACD, Li Heparin or Na Citrate on R. equi growth. These AC significantly (p < 0.05) delayed growth for 12 h following opsonization. The number of R. equi colonies after macrophage infection was significantly (p < 0.05) lower 72 h post-opsonization with Na Citrate. K

Indexed as

Actinomycetales InfectionsHorse DiseasesRhodococcus equiAnimalsAntibodies, BacterialAnticoagulantsHorsesAntibodies, BacterialAnticoagulantsAnticoagulantsCitrateEDTAMacrophagesPlasmaPrescotella equiRhodococcus equi

Identifiers

PMID35164828
PMCPMC8842809
OpenAlexW4225783758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.