Observational studyBMC geriatrics2022
Frailty and functional dependence in older population: lessons from the FREEDOM Limousin - Nouvelle Aquitaine Cohort Study.
Observational study in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Frailty and outcomes in older adults hospitalized for epilepsy: a nationwide inpatient sample study.BMC geriatrics · 2026Article
- Oral health status and its relation to frailty in older adults: a cross-sectional study.BMC geriatrics · 2026Article
- Latent profile analysis of depressive symptoms among Chinese older adults with disabilities and associated factors.Frontiers in psychiatry · 2026Article
- Shaping older adults' care policy: a scoping review of key determinants in post-acute and community reintegration transitions.BMC health services research · 2025Article
- SANTANA Cohort: Study on Frailty in Institutionalised Older Adults and Its Relationship With Gordon's Functional Health Patterns.Journal of advanced nursing · 2025Article
- Association of functional impairment and frailty with the frequency of hospitalizations between sexes in a population aged 60+ years.Przeglad menopauzalny = Menopause review · 2025Article
- Article
- Neurocognitive outcomes and functional independence in adult survivors of childhood medulloblastoma diagnosed over 3 decades.Neuro-oncology · 2025Article
- Uncovering unseen ties: a network analysis explores activities of daily living limitations and depression among Chinese older adults.Frontiers in aging neuroscience · 2025Article
- Impact of a minimally invasive approach for colon cancer surgery on outcomes in patients with functional limitations.Colorectal cancer · 2025Article
- An Investigation of the Risk Factors Related to Frailty in Older Adults Receiving Home Care Services.Nutrients · 2024Article
- The Effects of Cognitive Ability, Mental Health, and Self-Quarantining on Functional Ability of Older Adults During the COVID-19 Pandemic: Results From the Canadian Longitudinal Study on Aging.Journal of geriatric psychiatry and neurology · 2024Article
- Frailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction.Journal of clinical medicine · 2024Article
- Factors Determining the Occurrence of Frailty Syndrome in Hospitalized Older Patients.International journal of environmental research and public health · 2022Article
- Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study.BMC geriatrics · 2022Article
- Geriatric Cardiology: Coming of Age.JACC. Advances · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMonitoring frailty indicators in elderly people is recommended to identify those who could benefit from disability prevention programs. To contribute to the understanding of the development of frailty in the elderly, we have created the FREEDOM-LNA cohort constituting an observational study of ageing in general population. Here, we described the characteristics of a cohort of elderly subjects who are followed for determination of frailty and loss of independence trajectories.
resultsThe cohort was composed of 1085 subjects in advanced age (mean: 83.7 ± 6.0 years) and of women in majority (68.3%). Cardiovascular risk factors were present in 88.4% of subjects. Abnormal musculoskeletal signs were reported in 44.0% and neurologic signs in 31.9%. There were 44.8% of subjects at risk of malnutrition (MNA <24) and 73.3% (668/911) at risk of mobility-related disability (SPPB ≤9); 39% (384/973) of subjects had impaired cognitive function (MMSE< 24, adjusted on education) and 49.0% (397/810) had signs of depression (GDS >9); 31.8% (240/753) were frail and 58.3% were pre-frail. Most subjects had at least one disability in ADL (66.9%) and IADL (85.1%). The SMAF indicated a loss of independence in 59.6%. Overall, 59.9% of subjects could not stay at home without at least some help. Consequently, a medical consultation was proposed in 68.2 and 42.1% social supports.
conclusionsA large part of this cohort was frail or pre-frail and presented signs of loss of independence, which may be explained by multiple factors including impaired health status, poor physical performance, cognition, isolation, depression, or nutrition. This cohort will help to determine factors that adversely influence the trajectory of physical frailty over time.
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