Evidence map›Paper›PMID 35164680›Full record

ArticleBMC geriatrics2022

The interplay between infection risk factors of SARS-CoV-2 and mortality: a cross-sectional study from a cohort of long-term care nursing home residents.

Laura Soldevila, Núria Prat, Miquel À Mas, Mireia Massot, Ramón Miralles, Josep M Bonet-Simó, Mar Isnard, Marta Expósito-Izquierdo, Irene Garcia-Sanchez, Sara Rodoreda-Noguerola and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Laura SoldevilaInternational Health Program, Regió Sanitària Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.
Núria PratDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Miquel À MasDirecció Clínica Territorial de Cronicitat Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.
Mireia MassotDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Ramón MirallesDirecció Clínica Territorial de Cronicitat Metropolitana Nord, Institut Català de la Salut, Badalona, Spain.
Josep M Bonet-SimóDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Mar IsnardDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Marta Expósito-IzquierdoDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Irene Garcia-SanchezDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Sara Rodoreda-NoguerolaDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Nemesio MorenoDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Esther BadiaDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Genís LópezDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Javier SevillaDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Oriol EstradaDirecció d'Atenció Primària Metropolitana Nord, Institut Català de la Salut, Sabadell, Spain.
Xavier VallèsInternational Health Program, Regió Sanitària Metropolitana Nord, Institut Català de la Salut, Badalona, Spain. xvallesc.mn.ics@gencat.cat.
Institut Català de la Salut · ESFundació Lluita contra les Infeccions · ESInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCovid-19 pandemic has particularly affected older people living in Long-term Care settings in terms of infection and mortality.

methodsWe carried out a cross-sectional analysis within a cohort of Long-term care nursing home residents between March first and June thirty, 2020, who were ≥ 65 years old and on whom at least one PCR test was performed. Socio-demographic, comorbidities, and clinical data were recorded. Facility size and community incidence of SARS-CoV-2 were also considered. The outcomes of interest were infection (PCR positive) and death.

resultsA total of 8021 residents were included from 168 facilities. Mean age was 86.4 years (SD = 7.4). Women represented 74.1%. SARS-CoV-2 infection was detected in 27.7% of participants, and the overall case fatality rate was 11.3% (24.9% among those with a positive PCR test). Epidemiological factors related to risk of infection were larger facility size (pooled aOR 1.73; P < .001), higher community incidence (pooled aOR 1.67, P = .04), leading to a higher risk than the clinical factor of low level of functional dependence (aOR 1.22, P = .03). Epidemiological risk factors associated with mortality were male gender (aOR 1.75; P < .001), age (pooled aOR 1.16; P < .001), and higher community incidence (pooled aOR 1.19, P = < 0.001) whereas clinical factors were low level of functional dependence (aOR 2.42, P < .001), Complex Chronic Condition (aOR 1.29, P < .001) and dementia (aOR 1.33, P <0.001). There was evidence of clustering for facility and health area when considering the risk of infection and mortality (P < .001).

conclusionsOur results suggest a complex interplay between structural and individual factors regarding Covid-19 infection and its impact on mortality in nursing-home residents.

Indexed as

COVID-19SARS-CoV-2AgedAged, 80 and overCross-Sectional StudiesFemaleHumansLong-Term CareMaleNursing HomesPandemicsRisk FactorsCovid-19EpidemiologyLong-term care nursing homesMortalitySARS-CoV-2

Identifiers

PMID35164680
PMCPMC8842505
OpenAlexW4212773044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.