ArticleClinical and experimental immunology1986
IgA mesangial deposits in C3H/HeJ mice after oral immunization with ferritin or bovine serum albumin.
Article in Clinical and experimental immunology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 24 citations in OpenAlex.
- Immunopathogenesis of experimental IgA nephropathy.Springer seminars in immunopathology · 1994Review
- IgA-containing immune complexes after challenge with food antigens in patients with IgA nephropathy.Clinical and experimental immunology · 1992Article
- Detection and characterization of circulating and glomerular immune complexes in experimental IgA nephropathy.Immunology · 1990Article
- Defective hepatic handling of IgA immune aggregates by mice with experimental IgA nephropathy.Immunology · 1989Article
- Contrasuppression in the mucosal immune system.Immunologic research · 1988Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to study an experimental model of IgA nephropathy, C3H/HeJ mice which are high IgA responders were strongly immunized orally with ferritin and compared to syngeneic C3H/eB. C3H/HeJ exhibited a significant increase of total IgA level in the serum and of IgA deposits in the mesangium. However the low level of IgA antibody to ferritin detected in the serum and the unsuccessful search for ferritin and antibody to ferritin in the glomeruli suggest that strong oral immunization of C3H/HeJ mice leads to high level of non specific IgA in the serum and deposition of IgA in the kidney.
Indexed as
Identifiers
3516467PMC1577390W2411389241What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.