Evidence map›Paper›PMID 35164566›Full record

ArticlemBio2021

Molecular Basis of Rhodomyrtone Resistance in Staphylococcus aureus.

Li Huang, Miki Matsuo, Carlos Calderón, Sook-Ha Fan, Aparna Viswanathan Ammanath, Xiaoqing Fu, Ningna Li, Arif Luqman, Marvin Ullrich, Florian Herrmann and 6 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Phenotypic and genetic stepwise changes inAntimicrobial agents and chemotherapy · 2025
    Article
  5. Rhodomyrtone-rich fractions fromVeterinary world · 2025
    Article
  6. Review
  7. Rhodomyrtone: a new anti-JAC-antimicrobial resistance · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Li Huang *Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Miki Matsuo *Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Carlos Calderón *Institute of Pharmaceutical Sciences, University of Tübingen, Tübingen, Germany.
Sook-Ha FanMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Aparna Viswanathan AmmanathMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Xiaoqing FuInstitute of Pharmaceutical Sciences, University of Tübingen, Tübingen, Germany.
Ningna LiMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Arif LuqmanMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Marvin UllrichInstitute of Organic Chemistry, University of Tübingen, Tübingen, Germany.
Florian HerrmannInstitute of Organic Chemistry, University of Tübingen, Tübingen, Germany.
Martin MaierInstitute of Organic Chemistry, University of Tübingen, Tübingen, Germany.
Anchun ChengInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural Universitygrid.80510.3c, Chengdu, China.ORCID 0000-0001-6093-353X
Fajun ZhangInstitute of Applied Physics, University of Tübingen, Tübingen, Germany.
Filipp OesterheltMicrobial Bioactive Compounds, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.
Michael LämmerhoferInstitute of Pharmaceutical Sciences, University of Tübingen, Tübingen, Germany.
Friedrich GötzMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.ORCID 0000-0002-2042-0518
University of Tübingen · DESichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhodomyrtone (Rom) is a plant-derived broad-spectrum antibiotic active against many Gram-positive pathogens. A single point mutation in the regulatory

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsDrug Resistance, BacterialStaphylococcus aureusXanthonesBacterial ProteinsMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective AgentsBacterial ProteinsrhodomyrtoneXanthonesFarEfarRFarRisothermal titration calorimetrylipidomic analysisP-lipidsresistance mechanismrhodomyrtoneRomStaphylococcus

Identifiers

PMID35164566
PMCPMC8844917
OpenAlexW4213089623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.