Evidence map›Paper›PMID 35164356›Full record

ArticleMolecules (Basel, Switzerland)2022

Four New Anthraquinones with Histone Deacetylase Inhibitory Activity from

Nattika Hangsamai, Kanokwan Photai, Thidathep Mahaamnart, Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Thanaset Senawong, Siripit Pitchuanchom, Mongkol Nontakitticharoen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Exploring new quinoxaline, quinoline, and naphthalene carboxamides as HDAC-targeted anticancer agents: Cytotoxicity, enzymatic HDAC evaluation, and in silico studies.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nattika HangsamaiNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Kanokwan PhotaiNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Thidathep MahaamnartNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Somdej KanokmedhakulNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Kwanjai KanokmedhakulNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Thanaset SenawongNatural Products Research Unit, Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Siripit PitchuanchomDepartment of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahasarakham University, Maha Sarakham 44150, Thailand.ORCID 0000-0001-7712-152X
Mongkol NontakitticharoenNatural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-2931-5917

Funding

Program Management Unit for Human Resources & Institutional Development, Research and Innovation (PMUB) through Khon Kaen University B05F630053
6 · The paper itself

Abstract

Chromatographic separation of the crude extracts from the roots of

Indexed as

AnthraquinonesCell ProliferationHistone Deacetylase InhibitorsHistone DeacetylasesHumansMolecular Docking SimulationMolecular StructureNeoplasmsPlant ExtractsPlant RootsRhamnaceaeTumor Cells, CulturedAnthraquinonesHistone Deacetylase InhibitorsHistone DeacetylasesPlant ExtractsanthraquinonecytotoxicityHDAC inhibitorVentilago denticulata

Identifiers

PMID35164356
PMCPMC8839831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.