Evidence map›Paper›PMID 35164334›Full record

ArticleMolecules (Basel, Switzerland)2022

Preliminary Studies of Antimicrobial Activity of New Synthesized Hybrids of 2-Thiohydantoin and 2-Quinolone Derivatives Activated with Blue Light.

Agnieszka Kania, Waldemar Tejchman, Anna M Pawlak, Krystian Mokrzyński, Bartosz Różanowski, Bogdan M Musielak, Magdalena Greczek-Stachura

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

  1. Synthesis, crystal structure and Hirshfeld surface analysis of 2-(2,5-dioxo-4,4-di-phenyl-imidazolidin-1-yl)-Acta crystallographica. Section E, Crystallographic communications · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. One-Pot High-throughput Synthesis ofTetrahedron letters · 2022
    Article
  8. Design and Synthesis of New Pyrimidine-Quinolone Hybrids as NovelPharmaceuticals (Basel, Switzerland) · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Agnieszka KaniaInstitute of Biology, Pedagogical University of Krakow, Podchorążych 2, 30-084 Kraków, Poland.ORCID 0000-0003-2986-0592
Waldemar TejchmanInstitute of Biology, Pedagogical University of Krakow, Podchorążych 2, 30-084 Kraków, Poland.ORCID 0000-0001-8336-4288
Anna M PawlakDepartment of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.ORCID 0000-0002-2911-6125
Krystian MokrzyńskiDepartment of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.ORCID 0000-0001-8092-9132
Bartosz RóżanowskiInstitute of Biology, Pedagogical University of Krakow, Podchorążych 2, 30-084 Kraków, Poland.ORCID 0000-0002-6362-1758
Bogdan M MusielakDepartment of Organic Chemistry, Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.ORCID 0000-0002-1665-5920
Magdalena Greczek-StachuraInstitute of Biology, Pedagogical University of Krakow, Podchorążych 2, 30-084 Kraków, Poland.
Uniwersytet Komisji Edukacji Narodowej w Krakowie · PLJagiellonian University · PL

Funding

Pedagogical University of Kraków BN.610-519/PBU/2020
6 · The paper itself

Abstract

Thiohydantoin and quinolone derivatives have attracted researchers' attention because of a broad spectrum of their medical applications. The aim of our research was to synthesize and analyze the antimicrobial properties of novel 2-thiohydantoin and 2-quinolone derivatives. For this purpose, two series of hybrid compounds were synthesized. Both series consisted of 2-thiohydantoin core and 2-quinolone derivative ring, however one of them was enriched with an acetic acid group at N3 atom in 2-thiohydantoin core. Antibacterial properties of these compounds were examined against bacteria:

Indexed as

Anti-Bacterial AgentsAntifungal AgentsGram-Negative BacteriaGram-Positive BacteriaLightMicrobial Sensitivity TestsMolecular StructurePhenalenesPseudomonas aeruginosaQuinolonesStructure-Activity RelationshipThiohydantoinsAnti-Bacterial AgentsAntifungal Agentsphenalen-1-onePhenalenesQuinolonesThiohydantoinsantibacterial test activityblue light activationhybrid of 2-thiohydantoin and 2-quinolone derivativesinglet oxygen generation

Identifiers

PMID35164334
PMCPMC8839260
OpenAlexW4210513325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.