Evidence map›Paper›PMID 35164253›Full record

ArticleMolecules (Basel, Switzerland)2022

In Vitro Assessment of the Cytotoxic and Antiproliferative Profile of Natural Preparations Containing Bergamot, Orange and Clove Essential Oils.

Vlad Tiberiu Alexa, Atena Galuscan, Codruța M Soica, Antoanela Cozma, Dorina Coricovac, Florin Borcan, Iuliana Popescu, Alexandra Mioc, Camelia Szuhanek, Cristina Adriana Dehelean and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

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  5. Review
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  8. In Vitro Determination of Cytotoxic Effects of Ten Essential Oils onInternational journal of molecular sciences · 2025
    Article
  9. In Vitro and In Silico Evaluation ofPlants (Basel, Switzerland) · 2024
    Article
  10. Article
  11. WasteAntioxidants (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Vlad Tiberiu AlexaDepartment of Preventive, Community Dentistry and Oral Health, Faculty of Dental Medicine, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-3920-6869
Atena GaluscanDepartment of Preventive, Community Dentistry and Oral Health, Faculty of Dental Medicine, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Codruța M SoicaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Antoanela CozmaDepartment of Soil Science, Faculty of Agriculture, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Calea Aradului No. 119, 300641 Timisoara, Romania.
Dorina CoricovacResearch Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy "Victor Babeș" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.ORCID 0000-0002-5760-8872
Florin BorcanDepartment of Analytical Chemistry, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-3406-0303
Iuliana PopescuDepartment of Soil Science, Faculty of Agriculture, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Calea Aradului No. 119, 300641 Timisoara, Romania.ORCID 0000-0002-5090-7431
Alexandra MiocDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0001-6459-2074
Camelia SzuhanekOrthodontic Research Center (ORTHO-CENTER), Faculty of Dental Medicine, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No 2, 300041 Timisoara, Romania.
Cristina Adriana DeheleanResearch Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy "Victor Babeș" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.
Daniela JumancaDepartment of Preventive, Community Dentistry and Oral Health, Faculty of Dental Medicine, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-2705-5020
Victor Babeș University of Medicine and Pharmacy Timișoara · ROUnivesity of Life Science "King Mihai I" from Timisoara · RO

Funding

This research was funded by "Victor Babeş" University of Medicine and Pharmacy, Timisoara, Romania, doctoral grant EODENT, UMFT/2019, Alexa Vlad Tiberiu. doctoral grant EODENT, UMFT/2019, Alexa Vlad Tiberiu.
6 · The paper itself

Abstract

Medicinal plants and essential oils (EOs), in particular, were intensively studied in recent years as viable alternatives for antiproliferative chemical synthetic agents. In the same lines, the present study focuses on investigating the effects of natural preparations (emulsions) based on EOs obtained from

Indexed as

Antineoplastic Agents, PhytogenicCell LineCell Line, TumorCell ProliferationCitrus sinensisClove OilDrug Screening Assays, AntitumorGas Chromatography-Mass SpectrometryHumansOils, VolatileAntineoplastic Agents, PhytogenicClove OilOils, Volatilecell viabilityCitrus bergamiaCitrus sinensisemulsionhuman melanoma cells (A375)human primary gingival fibroblasts (HGF)human squamous cell carcinoma (SCC-4)immortalized human keratinocytesSyzygium aromaticum

Identifiers

PMID35164253
PMCPMC8838259
OpenAlexW4210655976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.