Evidence map›Paper›PMID 35164247›Full record

ArticleMolecules (Basel, Switzerland)2022

New Experimental Conditions for Diels-Alder and Friedel-Crafts Alquilation Reactions with Thiophene: A New Selenocyanate with Potent Activity against Cancer.

Gorka Calvo-Martín, Daniel Plano, Carmen Sanmartín

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Stable Vicinal Bisketene Equivalents for Aryne Diels-Alder Reactions.Synlett : accounts and rapid communications in synthetic organic chemistry · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gorka Calvo-MartínDepartamento de Tecnología y Química Farmacéuticas, Facultad de Farmacia y Nutrición, Universidad de Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0003-2806-5183
Daniel PlanoDepartamento de Tecnología y Química Farmacéuticas, Facultad de Farmacia y Nutrición, Universidad de Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0002-8266-0445
Carmen SanmartínDepartamento de Tecnología y Química Farmacéuticas, Facultad de Farmacia y Nutrición, Universidad de Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0003-3431-7826
Navarre Institute of Health Research · ESUniversidad de Navarra · ES

Funding

Fundación Bancaria Caixa d'Estalvis i Pensions de BarcelonaNational University of Distance Education
6 · The paper itself

Abstract

The reactivity of thiophene in Diels-Alder reactions is investigated with different maleimide derivatives. In this paper, we have synthesized for the first time the Diels-Alder adducts of thiophene at room temperature and atmospheric pressure. Maleimido-thiophene adducts were promoted by AlCl

Indexed as

Antineoplastic AgentsCell CycleCell Line, TumorCyanatesCycloaddition ReactionDrug Screening Assays, AntitumorHumansLewis AcidsSelenium CompoundsThiophenesAntineoplastic AgentsCyanatesLewis AcidsSelenium Compoundsselenocyanic acidThiophenescancercycloaditionDiels–AlderFriedel–Crafts alquilationseleniumselenophenethiophene

Identifiers

PMID35164247
PMCPMC8839041
OpenAlexW4210336028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.