Evidence map›Paper›PMID 35164122›Full record

ArticleMolecules (Basel, Switzerland)2022

Expression, Purification, and Comparative Inhibition of

Salih Osman Mohammed, Sayed H El El Ashry, Asaad Khalid, Mohamed R Amer, Ahmed M Metwaly, Ibrahim H Eissa, Eslam B Elkaeed, Ahmed Elshobaky, Elsayed E Hafez

Open access · goldAbstract readComparative Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
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  6. PeerJ · 2024
    Article
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  9. New Anticancer Theobromine Derivative Targeting EGFRMolecules (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Jusanin, a New Flavonoid fromMolecules (Basel, Switzerland) · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Salih Osman MohammedMedicinal and Aromatic Plants and Traditional Medicine Research Institute, National Center for Research, Khartoum 11111, Sudan.
Sayed H El El AshryChemistry Department, Faculty of Science, Alexandria University, Alexandria 21568, Egypt.
Asaad KhalidMedicinal and Aromatic Plants and Traditional Medicine Research Institute, National Center for Research, Khartoum 11111, Sudan.ORCID 0000-0001-8734-2588
Mohamed R AmerChemistry Department, Faculty of Science, Alexandria University, Alexandria 21568, Egypt.
Ahmed M MetwalyPharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0001-8566-1980
Ibrahim H EissaPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-6955-2263
Eslam B ElkaeedDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Ad Diriyah, Riyadh 13713, Saudi Arabia.ORCID 0000-0002-2546-8035
Ahmed ElshobakyBotany Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
Elsayed E HafezPlant Protection and Biomolecular Diagnosis Department, City of Scientific Research and Technological Applications, ARADI, Alexandria 21934, Egypt.ORCID 0000-0003-4044-5103
Al-Azhar University · EGAlexandria University · EGNational Centre for Research · SDAlfaisal University · SACity of Scientific Research and Technological Applications · EGMansoura University · EG

Funding

Research center at AlMaarefa University for funding this work under TUMA project TUMA-2021-4
6 · The paper itself

Abstract

The urease enzyme has been an important target for the discovery of effective pharmacological and agricultural products. Thirteen regio-selectively alkylated benzimidazole-2-thione derivatives have been designed to carry the essential features of urease inhibitors. The urease enzyme was isolated from

Indexed as

Molecular Docking SimulationUreaseBacterial ProteinsBenzimidazolesEnzyme InhibitorsHelicobacter pyloriBacterial ProteinsBenzimidazolesEnzyme InhibitorsUreasebenzimidazole 2-thionemolecular dockingo-phenylenediaminerecombinant ureaseregioselectivityurease inhibition

Identifiers

PMID35164122
PMCPMC8838460
OpenAlexW4210306615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.