Evidence map›Paper›PMID 35164067›Full record

ArticleMolecules (Basel, Switzerland)2022

Novel Pyridothienopyrimidine Derivatives: Design, Synthesis and Biological Evaluation as Antimicrobial and Anticancer Agents.

Eman M Mohi El-Deen, Manal M Anwar, Amina A Abd El-Gwaad, Eman A Karam, Mohamed K El-Ashrey, Rafika R Kassab

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Innovative Amino-Functionalization of Pyrido[2,3-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Design, synthesis,RSC advances · 2023
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Eman M Mohi El-DeenDepartment of Therapeutic Chemistry, National Research Centre, Cairo 12622, Egypt.ORCID 0000-0002-1997-3254
Manal M AnwarDepartment of Therapeutic Chemistry, National Research Centre, Cairo 12622, Egypt.
Amina A Abd El-GwaadDepartment of Therapeutic Chemistry, National Research Centre, Cairo 12622, Egypt.
Eman A KaramDepartment of Microbial Chemistry, National Research Centre, Cairo 12622, Egypt.
Mohamed K El-AshreyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID 0000-0002-3548-3888
Rafika R KassabDepartment of Chemistry, Faculty of Science (Girls), Al-Azhar University, Cairo 11754, Egypt.
National Research Centre · EGAl-Azhar University · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing risk of antimicrobial resistance besides the continuous increase in the number of cancer patients represents a great threat to global health, which requires intensified efforts to discover new bioactive compounds to use as antimicrobial and anticancer agents. Thus, a new set of pyridothienopyrimidine derivatives

Indexed as

Anti-Infective AgentsAntineoplastic AgentsCell Line, TumorDrug DesignDrug DiscoveryHumansMolecular Docking SimulationNeoplasmsPyrimidinesAnti-Infective AgentsAntineoplastic AgentsPyrimidinesthienopyrimidineantimicrobial activitycyclization reactionsEGFR-PK inhibitionHepG-2 cellsMCF-7 cellsmolecular dockingpyridothienopyrimidinesthieno[2,3-b]pyridine

Identifiers

PMID35164067
PMCPMC8839448
OpenAlexW4210297086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.