Evidence map›Paper›PMID 35163995›Full record

ReviewMolecules (Basel, Switzerland)2022

Modern Methods of Pre-Treatment of Plant Material for the Extraction of Bioactive Compounds.

Aneta Krakowska-Sieprawska, Anna Kiełbasa, Katarzyna Rafińska, Magdalena Ligor, Bogusław Buszewski

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 168 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Supercritical Fluid Extraction of Ergosterol fromMolecules (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Valorization of Bayberry (Plants (Basel, Switzerland) · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. A deep dive into herbal extraction: Techniques, trends, and technological advancements.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2026
    Article
  15. Article
  16. Article
  17. Black Chokeberry Extracts (Molecules (Basel, Switzerland) · 2025
    Review
  18. Article
  19. Review
  20. Effect of Drying Methods on Bioactivity ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aneta Krakowska-SieprawskaDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7 St., PL-87100 Torun, Poland.
Anna KiełbasaDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7 St., PL-87100 Torun, Poland.
Katarzyna RafińskaDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7 St., PL-87100 Torun, Poland.
Magdalena LigorDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7 St., PL-87100 Torun, Poland.
Bogusław BuszewskiDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7 St., PL-87100 Torun, Poland.ORCID 0000-0002-5482-7500
Nicolaus Copernicus University · PL

Funding

National Center for Research and Development, Poland BIOSTRATEG 2/298205/9/NCBR/2016
6 · The paper itself

Abstract

In this review, recent advances in the methods of pre-treatment of plant material for the extraction of secondary metabolites with high biological activity are presented. The correct preparation of the material for extraction is as important as the selection of the extraction method. This step should prevent the degradation of bioactive compounds as well as the development of fungi and bacteria. Currently, the methods of preparation are expected to modify the particles of the plant material in such a way that will contribute to the release of bioactive compounds loosely bonded to cell wall polymers. This review presents a wide range of methods of preparing plant material, including drying, freeze-drying, convection drying, microwave vacuum drying, enzymatic processes, and fermentation. The influence of the particular methods on the structure of plant material particles, the level of preserved bioactive compounds, and the possibility of their release during the extraction were highlighted. The plant material pre-treatment techniques used were discussed with respect to the amount of compounds released during extraction as well their application in various industries interested in products with a high content of biologically active compounds, such as the pharmaceutical, cosmetics, and food industries.

Indexed as

DesiccationFood HandlingFreeze DryingMicrowavesPlantsPreservation, BiologicalVacuumconvection dryingdryingenzymatic processesfermentationfreeze-dryingmicrowave vacuum dryingplant materialsample preparation

Identifiers

PMID35163995
PMCPMC8840492
OpenAlexW4207074240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.