Evidence map›Paper›PMID 35163988›Full record

ArticleMolecules (Basel, Switzerland)2022

Separation and Enrichment of Alkaloids from Coptidis Rhizoma and Euodiae Fructus by Macroporous Resin and Evaluation of the Effect on Bile Reflux Gastritis Rats.

Yan-Ying Li, Jin-Lei Feng, Zheng Li, Xin-Yu Zang, Xiu-Wei Yang

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Enrichment of Alkaloids fromFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yan-Ying LiState Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Peking University, Beijing 101191, China.
Jin-Lei FengTCM R&D Center, Tianjin Increase Innovative Drug Co., Ltd., Tianjin 300382, China.
Zheng LiTCM R&D Center, Tianjin Increase Innovative Drug Co., Ltd., Tianjin 300382, China.
Xin-Yu ZangTCM R&D Center, Beijing Increase Pharm Co., Ltd., Beijing 102200, China.
Xiu-Wei YangState Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Peking University, Beijing 101191, China.
Tianjin Institute of Pharmaceutical Research (China) · CNPeking University · CN

Funding

Key Technology of the Development of Chinese Medicine Aerosol Inhalation Prepara-tion 'Yinhuang inhalation solution' 2020A050515006The National Key Research and Development Program of China 2018YFC1704500,2018YFC1704506
6 · The paper itself

Abstract

The Zuojin Pill consists of Coptidis Rhizoma (CR) and Euodiae Fructus (EF). It has been a classic prescription for the treatment of gastrointestinal diseases in China since ancient times. Alkaloids are considered to be its main pharmacologically active substances. The authors of the present study investigated the feasibility of preparing high purity total alkaloids (TAs) from CR and EF extracts separately and evaluated the effect for the treatment of bile reflux gastritis (BRG).

Indexed as

AlkaloidsAnimalsBile RefluxCoptisEvodiaGastritisRatsRats, Sprague-DawleyResins, PlantAlkaloidsResins, Plantbile reflux gastritisCoptidis Rhizomaenrichment and purificationEuodiae Fructusgastric pathologymacroporous resinratstotal alkaloidsUHPLC–DADUHPLC–ESI–QTOF-MS

Identifiers

PMID35163988
PMCPMC8839576
OpenAlexW4207069463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.