Evidence map›Paper›PMID 35163934›Full record

ReviewMolecules (Basel, Switzerland)2022

Tilianin: A Potential Natural Lead Molecule for New Drug Design and Development for the Treatment of Cardiovascular Disorders.

Farrah Syazana Khattulanuar, Mahendran Sekar, Shivkanya Fuloria, Siew Hua Gan, Nur Najihah Izzati Mat Rani, Subban Ravi, Kumarappan Chidambaram, M Yasmin Begum, Abul Kalam Azad, Srikanth Jeyabalan and 7 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Liver cancer wars: plant-derived polyphenols strike back.Medical oncology (Northwood, London, England) · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Anthropological significance ofEcology and evolution · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Farrah Syazana KhattulanuarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Perak, Malaysia.
Mahendran SekarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Perak, Malaysia.ORCID 0000-0002-3022-6137
Shivkanya FuloriaFaculty of Pharmacy, AIMST University, Bedong, Kedah 08100, Malaysia.
Siew Hua GanSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor 47500, Malaysia.ORCID 0000-0001-6470-3651
Nur Najihah Izzati Mat RaniFaculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Perak, Malaysia.
Subban RaviDepartment of Chemistry, Karpagam Academy of Higher Education, Coimbatore 641021, Tamil Nadu, India.
Kumarappan ChidambaramDepartment of Pharmacology, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.ORCID 0000-0002-7981-4562
M Yasmin BegumDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-1871-8585
Abul Kalam AzadFaculty of Pharmacy, AIMST University, Bedong, Kedah 08100, Malaysia.ORCID 0000-0003-4874-1169
Srikanth JeyabalanDepartment of Pharmacology, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 600116, Tamil Nadu, India.ORCID 0000-0003-3514-7654
Arulmozhi DhiravidamaniDepartment of Pharmacology, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 600116, Tamil Nadu, India.
Lakshmi ThangaveluCenter for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077, India.
Pei Teng LumDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh 30450, Perak, Malaysia.
Vetriselvan SubramaniyanFaculty of Medicine, Bioscience and Nursing, MAHSA University, Jalan SP 2, Bandar Saujana Putra, Jenjarom 42610, Selangor, Malaysia.ORCID 0000-0002-9629-9494
Yuan Seng WuCentre for Virus and Vaccine Research, School of Medical and Life Sciences, Sunway University, Subang Jaya 47500, Malaysia.ORCID 0000-0001-5574-8049
Kathiresan V SathasivamFaculty of Applied Sciences, AIMST University, Bedong, Kedah 08100, Malaysia.
Neeraj Kumar FuloriaFaculty of Pharmacy, AIMST University, Bedong, Kedah 08100, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disorders (CVDs) are the leading risk factor for death worldwide, and research into the processes and treatment regimens has received a lot of attention. Tilianin is a flavonoid glycoside that can be found in a wide range of medicinal plants and is most commonly obtained from

Indexed as

Drug DesignDrug DevelopmentAnimalsBiological ProductsCardiovascular DiseasesFlavonoidsGlycosidesHumansBiological ProductsFlavonoidsGlycosidestilianincardioprotectioncardiovascular disordersdrug developmentdrug-likenessmolecular mechanismtilianin

Identifiers

PMID35163934
PMCPMC8838974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.