Evidence map›Paper›PMID 35163932›Full record

ArticleMolecules (Basel, Switzerland)2022

Impact of a Shorter Brine Soaking Time on Nutrient Bioaccessibility and Peptide Formation in 30-Months-Ripened Parmigiano Reggiano Cheese.

Mattia Di Nunzio, Cecilia Loffi, Elena Chiarello, Luca Dellafiora, Gianfranco Picone, Giorgia Antonelli, Clarissa Di Gregorio, Francesco Capozzi, Tullia Tedeschi, Gianni Galaverna and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Mattia Di NunzioDepartment of Food, Environmental and Nutritional Sciences (Defens), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0001-8219-0191
Cecilia LoffiDepartment of Food and Drugs, University of Parma, Parco Area delle Scienze 95/A, 43124 Parma, Italy.ORCID 0000-0003-1794-9151
Elena ChiarelloDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy.ORCID 0000-0001-6272-5785
Luca DellafioraDepartment of Food and Drugs, University of Parma, Parco Area delle Scienze 95/A, 43124 Parma, Italy.ORCID 0000-0002-1901-3317
Gianfranco PiconeDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy.ORCID 0000-0001-7932-6692
Giorgia AntonelliDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy.ORCID 0000-0002-2065-5261
Clarissa Di GregorioInterdepartmental Centre for Industrial Agri-Food Research (CIRI), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy.
Francesco CapozziDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy.ORCID 0000-0002-5543-2359
Tullia TedeschiDepartment of Food and Drugs, University of Parma, Parco Area delle Scienze 95/A, 43124 Parma, Italy.
Gianni GalavernaDepartment of Food and Drugs, University of Parma, Parco Area delle Scienze 95/A, 43124 Parma, Italy.ORCID 0000-0001-9042-2378
Alessandra BordoniDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy.ORCID 0000-0003-4579-1662
University of Parma · ITCentre International de Recherche en Infectiologie · FRUniversity of Bologna · ITUniversity of Milan · IT

Funding

Innovative Milk and Meat products for Consumer's Health - MiMe4Health unavailable
6 · The paper itself

Abstract

Reducing the salt content in food is an important nutritional strategy for decreasing the risk of diet-related diseases. This strategy is particularly effective when applied to highly appreciated food having good nutritional characteristics, if it does not impact either upon sensory or nutritional properties of the final product. This work aimed at evaluating if the reduction of salt content by decreasing the brine soaking time modifies fatty acid and protein bioaccessibility and bioactive peptide formation in a 30-month-ripened Parmigiano Reggiano cheese (PRC). Hence, conventional and hyposodic PRC underwent in vitro static gastrointestinal digestion, and fatty acid and protein bioaccessibility were assessed. The release of peptide sequences during digestion was followed by LC-HRMS, and bioactive peptides were identified using a bioinformatic approach. At the end of digestion, fatty acid and protein bioaccessibility were similar in conventional and hyposodic PRC, but most of the bioactive peptides, mainly the ACE-inhibitors, were present in higher concentrations in the low-salt cheese. Considering that the sensory profiles were already evaluated as remarkably similar in conventional and hyposodic PRC, our results confirmed that shortening brine soaking time represents a promising strategy to reduce salt content in PRC.

Indexed as

Peptide BiosynthesisCheeseFood HandlingHumansNutrientsSaltsSodium ChlorideSolubilityWaterbrineNutrientsSaltsSodium ChlorideWaterbioaccessibilitybioactive peptidesin vitro digestionParmigiano Reggiano cheese

Identifiers

PMID35163932
PMCPMC8840655
OpenAlexW4206070441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.