Evidence map›Paper›PMID 35163909›Full record

ArticleMolecules (Basel, Switzerland)2022

Mapping the DNA Damaging Effects of Polypyridyl Copper Complexes with DNA Electrochemical Biosensors.

Anna Banasiak, Nicolò Zuin Fantoni, Andrew Kellett, John Colleran

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Uracil-Peptide-Pyrene Conjugates as CuChembiochem : a European journal of chemical biology · 2026
    Article
  2. Biomimetic Radical Chemistry and Applications.Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Anna BanasiakApplied Electrochemistry Group, FOCAS Institute, Technological University Dublin, Camden Row, Dublin 8, D08 CKP1 Dublin, Ireland.ORCID 0000-0002-0867-3635
Nicolò Zuin FantoniDepartment of Chemistry, University of Oxford, Oxford OX1 3TA, UK.
Andrew KellettSchool of Chemical Sciences and National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, D09 NR58 Dublin, Ireland.ORCID 0000-0002-8947-1401
John ColleranApplied Electrochemistry Group, FOCAS Institute, Technological University Dublin, Camden Row, Dublin 8, D08 CKP1 Dublin, Ireland.ORCID 0000-0001-5694-9010
Technological University Dublin · IEDublin City University · IEUniversity of Oxford · GB

Funding

European Commission H2020-MSCA-ITN-2014--642023Science Foundation Ireland 12/RC/2275_P2Science Foundation Ireland SFI-CDA;15/CDA/3648Technological University Dublin Fiosraigh Award (PB03979)
6 · The paper itself

Abstract

Several classes of copper complexes are known to induce oxidative DNA damage that mediates cell death. These compounds are potentially useful anticancer agents and detailed investigation can reveal the mode of DNA interaction, binding strength, and type of oxidative lesion formed. We recently reported the development of a DNA electrochemical biosensor employed to quantify the DNA cleavage activity of the well-studied [Cu(phen)

Indexed as

Biosensing TechniquesCoordination ComplexesCopperCrystallography, X-RayDNADNA CleavageCoordination ComplexesCopperDNAchemical nucleasescopper complexesDNA biosensorDNA-drug interactionmetallodrugs

Identifiers

PMID35163909
PMCPMC8838702
OpenAlexW4205791611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.