Evidence map›Paper›PMID 35163854›Full record

ArticleMolecules (Basel, Switzerland)2022

Elucidation of Chemical Interactions between Crude Drugs Using Quantitative Thin-Layer Chromatography Analysis.

Naohiro Oshima, Maho Saito, Mina Niino, Yuki Hiraishi, Kana Ueki, Kazuki Okoshi, Takashi Hakamatsuka, Noriyasu Hada

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Naohiro OshimaFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Maho SaitoFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Mina NiinoFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Yuki HiraishiFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Kana UekiFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Kazuki OkoshiFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Takashi HakamatsukaDivision of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Science, Kawasaki 210-9501, Japan.
Noriyasu HadaFaculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.
Tokyo University of Science · JPNational Institute of Health Sciences · JP

Funding

Japan Agency for Medical Research and Development JP19mk0101102j0002.
6 · The paper itself

Abstract

To elucidate the interactions between crude drugs in Kampo medicines (traditional Japanese medicines), it is important to determine the content of the constituents in a cost-effective and simple manner. In this study, we quantified the constituents in crude drug extracts using thin-layer chromatography (TLC), an inexpensive and simple analytical method, to elucidate the chemical interactions between crude drugs. We focused on five crude drugs, for which quantitative high-performance liquid chromatography (HPLC) methods are stipulated in the Japanese Pharmacopoeia XVIII (JP XVIII) and compared the analytical data of HPLC and TLC, confirming that the TLC results corresponded with the HPLC data and satisfied the criteria of JP XVIII. (

Indexed as

Drug InteractionsMedicine, KampoChromatography, Thin LayerComplex MixturesDrugs, Chinese HerbalPhytochemicalsPlant ExtractsPlant RootsComplex MixturesDrugs, Chinese HerbalPhytochemicalsPlant Extractschemical interactioncrude drugsherbal-pair theorythin-layer chromatography

Identifiers

PMID35163854
PMCPMC8839786
OpenAlexW4205650561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.