DMSO and TMAO-Differences in Interactions in Aqueous Solutions of the K-Peptide.

Julia Godlewska, Bartosz Cieśla, Jarosław Wawer, Piotr Bruździak

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.6field-weighted citation impact, top 37% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

Characterizing Interactions Between Small Peptides and Dimethyl Sulfoxide Using Infrared Spectroscopy and Computational Methods.Molecules (Basel, Switzerland) · 2024
Article
Influence of Urea and Dimethyl Sulfoxide on K-Peptide Fibrillation.International journal of molecular sciences · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julia GodlewskaDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-5283-7510

Bartosz CieślaDepartment of Inorganic Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-1516-6797

Jarosław WawerDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0003-4033-6695

Piotr BruździakDepartment of Physical Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.ORCID 0000-0002-6445-0743

Gdańsk University of Technology · PL

Funding

National Science Center 2017/26/D/NZ1/00497

6 · The paper itself

Abstract

Interactions between a solvent and their co-solute molecules in solutions of peptides are crucial for their stability and structure. The K-peptide is a synthetic fragment of a larger hen egg white lysozyme protein that is believed to be able to aggregate into amyloid structures. In this study, a complex experimental and theoretical approach is applied to study systems comprising the peptide, water, and two co-solutes: trimethylamide

Indexed as

Calorimetry, Differential ScanningDensity Functional TheoryDimethyl SulfoxideMethylaminesPeptidesSpectroscopy, Fourier Transform InfraredWaterDimethyl SulfoxideMethylaminesPeptidestrimethyloxamineWateramyloidbiomolecular interactionschaperonesDFT calculationsintermolecular interactionsmicrocalorimetryprotein—ligand bindingspectroscopic techniques

Identifiers

PMID35163792

DOI10.3390/ijms23031872

PMCPMC8836737

OpenAlexW4210908395

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.