Evidence map›Paper›PMID 35163782›Full record

ArticleInternational journal of molecular sciences2022

Collagen Peptide in a Combinatorial Treatment with

Hee-Young Jung, Jian-Na Cai, Sung Chul Yoo, Seon-Hwa Kim, Jae-Gyu Jeon, Dongyeop Kim

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06063239 (Probiotics in Special Needs Patients at High Risk for Tooth Decay), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06063239 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial.

TypeinterventionalSponsorG. d'Annunzio UniversityRan2023 to 2024Enrolled70ConditionsTooth Decay, Intellectual Disability, Caries,DentalArmsTest Group, Positive Control, Negative Control
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Unveiling the dual nature ofFrontiers in oral health · 2025
    Pooled it
  2. HApplied and environmental microbiology · 2026
    Article
  3. Effects of Oral Probiotics onDentistry journal · 2026
    Review
  4. Asiatic Acid Disrupts the Biofilm Virulence ofInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Effects ofFoods (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hee-Young JungDepartment of Preventive Dentistry, School of Dentistry, Jeonbuk National University, Jeonju 54896, Korea.
Jian-Na CaiDepartment of Preventive Dentistry, School of Dentistry, Jeonbuk National University, Jeonju 54896, Korea.
Sung Chul YooVixxol Corporation, Gunpo 15807, Korea.
Seon-Hwa KimVixxol Corporation, Gunpo 15807, Korea.
Jae-Gyu JeonDepartment of Preventive Dentistry, School of Dentistry, Jeonbuk National University, Jeonju 54896, Korea.
Dongyeop KimDepartment of Preventive Dentistry, School of Dentistry, Jeonbuk National University, Jeonju 54896, Korea.ORCID 0000-0002-6185-9463
Jeonbuk National University · KR

Funding

Jeonbuk National University Research funds for newly appointed professorsNational Research Foundation of Korea 2021R1C1C1005317Vixxol Corporation Research Fund
6 · The paper itself

Abstract

Dental caries is caused by the formation of cariogenic biofilm, leading to localized areas of enamel demineralization.

Indexed as

AcidsBacterial ProteinsBiofilmsCollagenCombined Modality TherapyCulture MediaDental CariesGene Expression ProfilingGene Expression Regulation, BacterialHumansHydrogen-Ion ConcentrationLacticaseibacillus rhamnosusMicroscopy, ConfocalPeptidesPolysaccharides, BacterialProbioticsAcidsBacterial ProteinsCollagenCulture Mediaexopolysaccharide, StreptococcusPeptidesPolysaccharides, Bacterialacidogenicityaciduricitycariogenic biofilmsmetabolic interferenceprebioticsprobioticssynbiotics

Identifiers

PMID35163782
PMCPMC8837136
OpenAlexW4210822461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.