Evidence map›Paper›PMID 35163714›Full record

ArticleInternational journal of molecular sciences2022

Enhanced Tumor Imaging Using Glucosamine-Conjugated Polyacrylic Acid-Coated Ultrasmall Gadolinium Oxide Nanoparticles in Magnetic Resonance Imaging.

Shuwen Liu, Huan Yue, Son Long Ho, Soyeon Kim, Ji Ae Park, Tirusew Tegafaw, Mohammad Yaseen Ahmad, Seungho Kim, Abdullah Khamis Ali Al Saidi, Dejun Zhao and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Tumor-Targeting TACS omega · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Shuwen LiuDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.
Huan YueDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.
Son Long HoDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.ORCID 0000-0001-7175-246X
Soyeon KimDivision of RI-Convergence Research, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul 01817, Korea.ORCID 0000-0002-4386-1543
Ji Ae ParkDivision of RI-Convergence Research, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul 01817, Korea.ORCID 0000-0001-6109-802X
Tirusew TegafawDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.ORCID 0000-0001-7730-5636
Mohammad Yaseen AhmadDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.ORCID 0000-0002-6754-5764
Seungho KimDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Taegu 41944, Korea.
Abdullah Khamis Ali Al SaidiDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.ORCID 0000-0002-9179-9991
Dejun ZhaoDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.
Ying LiuDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.
Sung-Wook NamDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Taegu 41944, Korea.ORCID 0000-0002-2306-6032
Kwon Seok ChaeDepartment of Biology Education, Teachers' College, Kyungpook National University, Taegu 41566, Korea.ORCID 0000-0001-5051-0699
Yongmin ChangDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Taegu 41944, Korea.
Gang Ho LeeDepartment of Chemistry, College of Natural Sciences, Kyungpook National University, Taegu 41566, Korea.ORCID 0000-0001-7451-6366
Kyungpook National University · KRKorea Institute of Radiological and Medical Sciences · KR

Funding

National Research Foundation of Korea 2016R1D1A3B01007622National Research Foundation of Korea 2021R1A4A1029433
6 · The paper itself

Abstract

Owing to a higher demand for glucosamine (GlcN) in metabolic processes in tumor cells than in normal cells (i.e., GlcN effects), tumor imaging in magnetic resonance imaging (MRI) can be highly improved using GlcN-conjugated MRI contrast agents. Here, GlcN was conjugated with polyacrylic acid (PAA)-coated ultrasmall gadolinium oxide nanoparticles (UGONs) (d

Indexed as

NanoparticlesNeoplasmsAcrylic ResinsAnimalsContrast MediaGadoliniumGlucosamineMagnetic Resonance ImagingMiceAcrylic Resinscarbopol 940Contrast MediaGadoliniumgadolinium oxideGlucosamineenhanced tumor imagingGlcN effectsglucosaminemagnetic resonance imagingultrasmall gadolinium oxide nanoparticle

Identifiers

PMID35163714
PMCPMC8836488
OpenAlexW4210557137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.