Evidence map›Paper›PMID 35163671›Full record

ArticleInternational journal of molecular sciences2022

Histological Grade and Tumor Stage Are Correlated with Expression of Receptor Activator of Nuclear Factor Kappa b (Rank) in Epithelial Ovarian Cancers.

Raul Gomez, Miguel Á Tejada, Víctor Rodríguez-García, Octavio Burgués, Ana I Santos-Llamas, Andrea Martínez-Massa, Antonio Marín-Montes, Juan J Tarín, Antonio Cano

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Raul GomezResearch Unit on Women's Health-Institute of Health Research, INCLIVA, 46010 Valencia, Spain.ORCID 0000-0002-3798-5961
Miguel Á TejadaResearch Unit on Women's Health-Institute of Health Research, INCLIVA, 46010 Valencia, Spain.ORCID 0000-0002-9323-7626
Víctor Rodríguez-GarcíaDepartment of Pediatrics and Obstetrics and Gynecology, University of Valencia, 46010 Valencia, Spain.
Octavio BurguésDepartment of Pathology, Hospital Clinico Universitario, 46010 Valencia, Spain.
Ana I Santos-LlamasResearch Unit on Women's Health-Institute of Health Research, INCLIVA, 46010 Valencia, Spain.
Andrea Martínez-MassaService of Obstetrics and Gynecology, Hospital Clínico Universitario, Av Blasco Ibáñez 17, 46010 Valencia, Spain.
Antonio Marín-MontesService of Obstetrics and Gynecology, Hospital Clínico Universitario, Av Blasco Ibáñez 17, 46010 Valencia, Spain.
Juan J TarínResearch Unit on Women's Health-Institute of Health Research, INCLIVA, 46010 Valencia, Spain.
Antonio CanoResearch Unit on Women's Health-Institute of Health Research, INCLIVA, 46010 Valencia, Spain.ORCID 0000-0001-8046-0303
Universitat de València · ESHospital Clínico Universitario de Valencia · ESINCLIVA Health Research Institute · ES

Funding

Instituto de Salud Carlos III PI17/02329 and PI20/01835Ministry of Economy, Industry and Competitiveness CPII18/00037
6 · The paper itself

Abstract

The receptor activator of nuclear factor kappa B (RANK) is becoming recognized as a master regulator of tumorigenesis, yet its role in gynecological cancers remains mostly unexplored. We investigated whether there is a gradation of RANK protein and mRNA expression in epithelial ovarian cancer (EOC) according to malignancy and tumor staging. Immunohistochemical expression of RANK was examined in a cohort of 135 (benign

Indexed as

Carcinoma, Ovarian EpithelialCell Line, TumorFemaleGene Expression Regulation, NeoplasticHumansNeoplasm GradingNeoplasm StagingOvarian NeoplasmsReceptor Activator of Nuclear Factor-kappa BRNA, MessengerReceptor Activator of Nuclear Factor-kappa BRNA, Messengerepithelial ovarian cancersimmunohistochemistryRANKtumor stage, tumor grade

Identifiers

PMID35163671
PMCPMC8836022
OpenAlexW4210304180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.