ReviewInternational journal of molecular sciences2022
Metalloprotein-Specific or Critical Amino Acid Residues: Perspectives on Plant-Precise Detoxification and Recognition Mechanisms under Cadmium Stress.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 51 citations in OpenAlex.
- Article
- Jasmonic Acid and Salicylic Acid in Regulating Plant Cadmium Accumulation and Tolerance: Mechanisms and Crosstalk.Plants (Basel, Switzerland) · 2026Review
- Plant electrical signals reveal the joint interactions of bicarbonate- selenium on cadmium transport inPlant signaling & behavior · 2025Article
- Genome-wide identification and evolutionary analysis of NRAMP family genes in tomato (Solanum lycopersicum L.) under cadmium and salt stress.BMC genomics · 2025Article
- Characterization of Cd and As accumulation and subcellular distribution in different varieties of perennial ryegrasses.BMC plant biology · 2025Article
- Utilization of Antagonistic Interactions Between Micronutrients and Cadmium (Cd) to Alleviate Cd Toxicity and Accumulation in Crops.Plants (Basel, Switzerland) · 2025Review
- Chemical Synthesis and Insecticidal Activity Research Based on α-Conotoxins.Molecules (Basel, Switzerland) · 2024Article
- Transcriptomics, proteomics, and metabolomics interventions prompt crop improvement against metal(loid) toxicity.Plant cell reports · 2024Review
- Unraveling the Mechanism of StWRKY6 in Potato (Foods (Basel, Switzerland) · 2023Article
- Abscisic-Acid-Regulated Responses to Alleviate Cadmium Toxicity in Plants.Plants (Basel, Switzerland) · 2023Review
- UVB-Pretreatment-Enhanced Cadmium Absorption and Enrichment in Poplar Plants.International journal of molecular sciences · 2022Article
- Identification of the Major Effector StSROs in Potato: A PotentialInternational journal of molecular sciences · 2022Article
- Chemical forms of cadmium in soil and its distribution in French marigold sub-cells in response to chelator GLDA.Scientific reports · 2022Article
- Reprisal ofFrontiers in plant science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Cadmium (Cd) pollution in cultivated land is caused by irresistible geological factors and human activities; intense diffusion and migration have seriously affected the safety of food crops. Plants have evolved mechanisms to control excessive influx of Cd in the environment, such as directional transport, chelation and detoxification. This is done by some specific metalloproteins, whose key amino acid motifs have been investigated by scientists one by one. The application of powerful cell biology, crystal structure science, and molecular probe targeted labeling technology has identified a series of protein families involved in the influx, transport and detoxification of the heavy metal Cd. This review summarizes them as influx proteins (NRAMP, ZIP), chelating proteins (MT, PDF), vacuolar proteins (CAX, ABCC, MTP), long-distance transport proteins (OPT, HMA) and efflux proteins (PCR, ABCG). We selected representative proteins from each family, and compared their amino acid sequence, motif structure, subcellular location, tissue specific distribution and other characteristics of differences and common points, so as to summarize the key residues of the Cd binding target. Then, we explain its special mechanism of action from the molecular structure. In conclusion, this review is expected to provide a reference for the exploration of key amino acid targets of Cd, and lay a foundation for the intelligent design and breeding of crops with high/low Cd accumulation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.