Evidence map›Paper›PMID 35163587›Full record

ArticleInternational journal of molecular sciences2022

Genome-Wide DNA Methylation in Policemen Working in Cities Differing by Major Sources of Air Pollution.

Katerina Honkova, Andrea Rossnerova, Irena Chvojkova, Alena Milcova, Hasmik Margaryan, Anna Pastorkova, Antonin Ambroz, Pavel Rossner, Vitezslav Jirik, Jiri Rubes and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  9. Article
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  11. Pilot Study of the Long-Term Effects of Radiofrequency Electromagnetic Radiation Exposure on the Mouse Brain.International journal of environmental research and public health · 2023
    Article
  12. Article
  13. Review
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  16. Toxicogenomics and Molecular Markers in Pollution.International journal of molecular sciences · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Katerina HonkovaDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.ORCID 0000-0002-5713-8161
Andrea RossnerovaDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Irena ChvojkovaDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Alena MilcovaDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Hasmik MargaryanDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Anna PastorkovaDepartment of Nanotoxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Antonin AmbrozDepartment of Nanotoxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Pavel RossnerDepartment of Nanotoxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.ORCID 0000-0001-6921-5446
Vitezslav JirikCentre for Epidemiological Research, Faculty of Medicine, University of Ostrava, Syllabova 19, 703 00 Ostrava, Czech Republic.ORCID 0000-0001-8387-4077
Jiri RubesVeterinary Research Institute, Hudcova 296/70, 621 00 Brno, Czech Republic.ORCID 0000-0001-8126-6721
Radim J SramDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.ORCID 0000-0002-2500-4572
Jan TopinkaDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine CAS, Videnska 1083, 142 20 Prague 4, Czech Republic.
Czech Academy of Sciences, Institute of Experimental Medicine · CZUniversity of Ostrava · CZVeterinary Research Institute · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is the most studied epigenetic mechanism that regulates gene expression, and it can serve as a useful biomarker of prior environmental exposure and future health outcomes. This study focused on DNA methylation profiles in a human cohort, comprising 125 nonsmoking city policemen (sampled twice), living and working in three localities (Prague, Ostrava and Ceske Budejovice) of the Czech Republic, who spent the majority of their working time outdoors. The main characterization of the localities, differing by major sources of air pollution, was defined by the stationary air pollution monitoring of PM2.5, B[a]P and NO

Indexed as

PoliceAdultAir PollutantsAir PollutionCzech RepublicDNA MethylationEnvironmental ExposureFemaleGenome-Wide Association StudyHumansMaleMiddle AgedAir Pollutantsair pollutionDNA methylationenvironmentepigeneticsmolecular epidemiology

Identifiers

PMID35163587
PMCPMC8915177
OpenAlexW4210505451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.