Evidence map›Paper›PMID 35163519›Full record

ArticleInternational journal of molecular sciences2022

Structural Insights into the Substrate Transport Mechanisms in GTR Transporters through Ensemble Docking.

Carlos Peña-Varas, Christa Kanstrup, Ariela Vergara-Jaque, Mariela González-Avendaño, Christoph Crocoll, Osman Mirza, Ingo Dreyer, Hussam Nour-Eldin, David Ramírez

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Biological Activities of Glucosinolate and Its Enzymatic Product inInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Carlos Peña-VarasInstituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Llano Subercaseaux 2801-piso 6, Santiago 8900000, Chile.ORCID 0000-0003-2741-8813
Christa KanstrupDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg, Denmark.
Ariela Vergara-JaqueCenter for Bioinformatics, Simulation and Modeling (CBSM), Faculty of Engineering, Campus Talca, Universidad de Talca, 1 Poniente No. 1141, Casilla 721, Talca 3460000, Chile.
Mariela González-AvendañoCenter for Bioinformatics, Simulation and Modeling (CBSM), Faculty of Engineering, Campus Talca, Universidad de Talca, 1 Poniente No. 1141, Casilla 721, Talca 3460000, Chile.
Christoph CrocollDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg, Denmark.ORCID 0000-0003-2754-3518
Osman MirzaDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Ingo DreyerCenter for Bioinformatics, Simulation and Modeling (CBSM), Faculty of Engineering, Campus Talca, Universidad de Talca, 1 Poniente No. 1141, Casilla 721, Talca 3460000, Chile.ORCID 0000-0002-2781-0359
Hussam Nour-EldinDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg, Denmark.
David RamírezInstituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Llano Subercaseaux 2801-piso 6, Santiago 8900000, Chile.ORCID 0000-0003-0002-1189
University of Copenhagen · DKUniversity of Talca · CLUniversidad Autónoma de Chile · CL

Funding

Agencia Nacional de Investigación y Desarrollo ACT210012CONICYT Programa de Cooperación Internacional REDES190025CONICYT Programa de Cooperación Internacional REDES190074Danish National Research Foundation DNRF99Fondo Nacional de Desarrollo Científico y Tecnológico 11180604
6 · The paper itself

Abstract

Glucosinolate transporters (GTRs) are part of the nitrate/peptide transporter (NPF) family, members of which also transport specialized secondary metabolites as substrates. Glucosinolates are defense compounds derived from amino acids. We selected 4-methylthiobutyl (4MTB) and indol-3-ylmethyl (I3M) glucosinolates to study how GTR1 from

Indexed as

ArabidopsisArabidopsis ProteinsBiological TransportButyratesGlucosinolatesIndolesModels, MolecularMolecular Docking SimulationMonosaccharide Transport ProteinsProtein BindingProtein ConformationThioglucosides4-methylthiobutylglucosinolateArabidopsis ProteinsButyratesglucobrassicinGlucosinolatesIndolesMonosaccharide Transport ProteinsThioglucosidesensemble dockingglucosinolatesGTRsmembrane protein modelingphytocompounds transport mechanism

Identifiers

PMID35163519
PMCPMC8836200
OpenAlexW4210273390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.