Evidence map›Paper›PMID 35163484›Full record

ArticleInternational journal of molecular sciences2022

YdfD, a Lysis Protein of the Qin Prophage, Is a Specific Inhibitor of the IspG-Catalyzed Step in the MEP Pathway of

Zhifang Lu, Biying Wang, Zhiyu Qiu, Ruiling Zhang, Jimin Zheng, Zongchao Jia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Genome-wide Screening of the Escherichia coli Keio Knockout Collection Identifies Genetic Determinants of Epetraborole Hypersusceptibility.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhifang LuCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID 0000-0003-4446-5259
Biying WangCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID 0000-0001-5207-8166
Zhiyu QiuCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID 0000-0002-3829-2243
Ruiling ZhangCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID 0000-0001-7033-2930
Jimin ZhengCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID 0000-0001-6242-152X
Zongchao JiaDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3N6, Canada.ORCID 0000-0002-9322-9394
Beijing Normal University · CNQueen's University · CA

Funding

National Natural Science Foundation of China 21773014Natural Sciences and Engineering Research Council of Canada RGPIN-2018-04427
6 · The paper itself

Abstract

Bacterial cryptic prophage (defective prophage) genes are known to drastically influence host physiology, such as causing cell growth arrest or lysis, upon expression. Many phages encode lytic proteins to destroy the cell envelope. As natural antibiotics, only a few lysis target proteins were identified.

Indexed as

BiocatalysisConserved SequenceCysteineErythritolEscherichia coliEscherichia coli ProteinsModels, BiologicalProphagesProtein BindingProtein Structure, SecondaryRNA, MessengerSolutionsStress, PhysiologicalSugar PhosphatesViral Proteins2-C-methylerythritol 4-phosphateCysteineErythritolEscherichia coli ProteinsRNA, MessengerSolutionsSugar PhosphatesViral ProteinsIspGlysisMEP pathwayprophageYdfD

Identifiers

PMID35163484
PMCPMC8835842
OpenAlexW4210251580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.