Evidence map›Paper›PMID 35163312›Full record

ArticleInternational journal of molecular sciences2022

Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs.

Hsin-Han Yang, I-Tsang Chiang, Jen-Wei Liu, Jeanne Hsieh, Jui-Hao Lee, Huai-En Lu, Hwa-Sung Tso, Yu-Chen Deng, Jo-Chi Kao, Jhen-Rong Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hsin-Han YangDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
I-Tsang ChiangDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
Jen-Wei LiuEverfront Biotech Inc., New Taipei City 221, Taiwan.
Jeanne HsiehEverfront Biotech Inc., New Taipei City 221, Taiwan.
Jui-Hao LeeEverfront Biotech Inc., New Taipei City 221, Taiwan.ORCID 0000-0001-5907-7246
Huai-En LuBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu 300, Taiwan.
Hwa-Sung TsoDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
Yu-Chen DengDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
Jo-Chi KaoDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
Jhen-Rong WuDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
Horng-Jyh HarnBioinnovation Center, Buddhist Tzu Chi Foundation, Hualien 970, Taiwan.
Tzyy-Wen ChiouDepartment of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
National Dong Hwa University · TWFood Industry Research and Development Institute · TWTzu Chi University · TW

Funding

Everfront Biotech Inc., New Taipei City 221, Taiwan CT103007
6 · The paper itself

Abstract

Spinocerebellar ataxia type 3 (SCA3) is characterized by the over-repetitive CAG codon in the ataxin-3 gene (

Indexed as

AnimalsAtaxin-3AutophagyCalpainCell DifferentiationCells, CulturedHumansInduced Pluripotent Stem CellsMachado-Joseph DiseaseMalePhthalic AnhydridesProteasome Endopeptidase ComplexPurkinje CellsRepressor ProteinsAtaxin-3ATXN3 protein, humanbutylidenephthalideCalpainPhthalic AnhydridesProteasome Endopeptidase ComplexRepressor ProteinsATXN3iPSCsn-butylidenephthalidePurkinje progenitorquinolinic acidSCA3

Identifiers

PMID35163312
PMCPMC8836169
OpenAlexW4210432084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.