Evidence map›Paper›PMID 35163229›Full record

ArticleInternational journal of molecular sciences2022

SEC23B Loss-of-Function Suppresses Hepcidin Expression by Impairing Glycosylation Pathway in Human Hepatic Cells.

Barbara Eleni Rosato, Roberta Marra, Vanessa D'Onofrio, Federica Del Giudice, Simone Della Monica, Achille Iolascon, Immacolata Andolfo, Roberta Russo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. New Cases and Mutations inInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. New Advances in Iron Metabolism, Ferritin and Hepcidin Research.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Barbara Eleni RosatoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.
Roberta MarraDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.
Vanessa D'OnofrioDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.
Federica Del GiudiceCEINGE Biotecnologie Avanzate, 80145 Napoli, Italy.
Simone Della MonicaDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.
Achille IolasconDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.ORCID 0000-0002-9558-0356
Immacolata AndolfoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.
Roberta RussoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Napoli, Italy.ORCID 0000-0002-3624-7721
Ceinge Biotecnologie Avanzate (Italy) · IT

Funding

European Hematology Association 3978026Programme STAR, financially supported by UNINA and Compagnia di San Paolo
6 · The paper itself

Abstract

Biallelic pathogenic variants in the

Indexed as

Cell LineEndoplasmic ReticulumErythropoiesisGlycosylationGolgi ApparatusHepatocytesHepcidinsHumansIron OverloadLiverLoss of Function MutationPhenotypeVesicular Transport ProteinsHepcidinsSEC23B protein, humanVesicular Transport Proteinscongenital dyserythropoietic anemiasglycosylationhepcidiniron metabolismSEC23B

Identifiers

PMID35163229
PMCPMC8835815
OpenAlexW4210630781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.