Evidence map›Paper›PMID 35163220›Full record

ArticleInternational journal of molecular sciences2022

Interaction between miR4749 and Human Serum Albumin as Revealed by Fluorescence, FRET, Atomic Force Spectroscopy and Computational Modelling.

Valentina Botti, Silvia Marrone, Salvatore Cannistraro, Anna Rita Bizzarri

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Valentina BottiBiophysics and Nanoscience Centre, Department of Ecology and Biology DEB, Università della Tuscia, Largo dell'Università, 01100 Viterbo, Italy.ORCID 0000-0002-3429-8891
Silvia MarroneBiophysics and Nanoscience Centre, Department of Ecology and Biology DEB, Università della Tuscia, Largo dell'Università, 01100 Viterbo, Italy.
Salvatore CannistraroBiophysics and Nanoscience Centre, Department of Ecology and Biology DEB, Università della Tuscia, Largo dell'Università, 01100 Viterbo, Italy.ORCID 0000-0002-0228-7311
Anna Rita BizzarriBiophysics and Nanoscience Centre, Department of Ecology and Biology DEB, Università della Tuscia, Largo dell'Università, 01100 Viterbo, Italy.ORCID 0000-0003-3298-6639
Università degli Studi della Tuscia · IT

Funding

Italian Association for Cancer Research 24450
6 · The paper itself

Abstract

The interaction of Human Serum Albumin (HSA) with the microRNA, miR4749, was investigated by Atomic Force Spectrscopy (AFS), static and time-resolved fluorescence spectroscopy and by computational methods. The formation of a HSA/miR4749 complex with an affinity of about 10

Indexed as

Binding SitesCircular DichroismComputational BiologyFluorescenceFluorescence Resonance Energy TransferHumansMicroRNAsMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingSerum Albumin, HumanSpectrometry, FluorescenceThermodynamicsMicroRNAsSerum Albumin, Humancomputational dockingfluorescence quenchingFRETHuman Serum AlbuminmiR4749

Identifiers

PMID35163220
PMCPMC8835948
OpenAlexW4210253268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.