Evidence map›Paper›PMID 35163197›Full record

ArticleInternational journal of molecular sciences2022

Comparative Assessment of Bacteriophage and Antibiotic Activity against Multidrug-Resistant

Natalia Kaźmierczak, Bartłomiej Grygorcewicz, Marta Roszak, Beata Bochentyn, Lidia Piechowicz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Isolation and Genomic Analysis ofAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Efficacy of Three Kayviruses AgainstAntibiotics (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based onInternational journal of molecular sciences · 2024
    Review
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  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Natalia KaźmierczakDepartment of Medical Microbiology, Faculty of Medicine, Medical University of Gdańsk, Dębowa 25, 80-204 Gdańsk, Poland.ORCID 0000-0002-3985-2572
Bartłomiej GrygorcewiczDepartment of Laboratory Medicine, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0002-0593-0069
Marta RoszakDepartment of Laboratory Medicine, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0002-7721-1223
Beata BochentynFaculty of Applied Physics and Mathematics, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.
Lidia PiechowiczDepartment of Medical Microbiology, Faculty of Medicine, Medical University of Gdańsk, Dębowa 25, 80-204 Gdańsk, Poland.
Gdańsk Medical University · PLPomeranian Medical University · PLGdańsk University of Technology · PL

Funding

Gdańsk Medical University MN-01-0320/08/289National Science Center 2018/29/N/ST8/01043
6 · The paper itself

Abstract

Problems connected with biofilm-related infections and antibiotic resistance necessitate the investigation and development of novel treatment strategies. Given their unique characteristics, one of the most promising alternatives to conventional antibiotics are bacteriophages. In the in vitro and in vivo larva model study, we demonstrate that phages vB_SauM-A, vB_SauM-C, and vB_SauM-D are effective antibiofilm agents. The exposure of biofilm to phages vB_SauM-A and vB_SauM-D led to 2-3 log reductions in the colony-forming unit number in most of the multidrug-resistant

Indexed as

Anti-Bacterial AgentsBacteriolysisBacteriophagesBiofilmsDrug Resistance, MultipleGenome, ViralMethicillin-Resistant Staphylococcus aureusPhage TherapyStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial Agentsantibiofilmantibioticantibiotic resistancebacteriophagesbiofilmphage therapy

Identifiers

PMID35163197
PMCPMC8836238
OpenAlexW4210425870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.