Evidence map›Paper›PMID 35163150›Full record

ArticleInternational journal of molecular sciences2022

Photodynamic Therapy and Multi-Modality Imaging of Up-Conversion Nanomaterial Doped with AuNPs.

Wei Zhang, Yanli Lu, Yang Zang, Jinhui Han, Qingyun Xiong, Jinping Xiong

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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  8. Synthesis of Rare-Earth Nanomaterials Ag-Doped NaYFNanomaterials (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei ZhangBeijing Key Laboratory of Electrochemical Process and Technology of Materials, School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.ORCID 0000-0003-1768-0885
Yanli LuBeijing Key Laboratory of Electrochemical Process and Technology of Materials, School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Yang ZangBeijing Key Laboratory of Electrochemical Process and Technology of Materials, School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Jinhui HanState Key Laboratory of Organic-Inorganic Composites, School of Chemical Engineering, School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Qingyun XiongBeijing Key Laboratory of Electrochemical Process and Technology of Materials, School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Jinping XiongBeijing Key Laboratory of Electrochemical Process and Technology of Materials, School of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.ORCID 0000-0001-8688-1774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two key concerns exist in contemporary cancer chemotherapy in clinic: limited therapeutic efficiency and substantial side effects in patients. In recent years, researchers have been investigating a revolutionary cancer treatment technique, and photodynamic therapy (PDT) has been proposed by many scholars. A drug for photodynamic cancer treatment was synthesized using the hydrothermal method, which has a high efficiency to release reactive oxygen species (ROS). It may also be utilized as a clear multi-modality bioimaging platform for photoacoustic imaging (PAI) due to its photothermal effect, computed tomography (CT), and magnetic resonance imaging (MRI). When compared to single-modality imaging, multi-modality imaging delivers far more thorough and precise details for cancer diagnosis. Furthermore, Au-doped up-conversion nanoparticles (UCNPs) have an exceptionally high luminous intensity. The Au-doped UCNPs, in particular, are non-toxic to tissues without laser at an 808 nm wavelength, endowing the as-prepared medications with outstanding therapeutic efficacy but exceptionally low side effects. These findings may encourage fresh effective imaging-guided approaches to meet the goal of photodynamic cancer therapy to be created.

Indexed as

Theranostic NanomedicineAnimalsApoptosisCell ProliferationFemaleGoldHumansMetal NanoparticlesMiceMice, Inbred BALB CMice, NudeMultimodal ImagingPhotoacoustic TechniquesPhotochemotherapyReactive Oxygen SpeciesTumor Cells, CulturedGoldReactive Oxygen Speciesmulti-modality imagingnanomaterialsphotodynamicup-conversion

Identifiers

PMID35163150
PMCPMC8835744

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.