Evidence map›Paper›PMID 35163142›Full record

ReviewInternational journal of molecular sciences2022

Adenosine Receptors in Neuropsychiatric Disorders: Fine Regulators of Neurotransmission and Potential Therapeutic Targets.

Silvia Pasquini, Chiara Contri, Stefania Merighi, Stefania Gessi, Pier Andrea Borea, Katia Varani, Fabrizio Vincenzi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cell-Type-Specific WTAP and ALKBH5-Mediated mCNS neuroscience & therapeutics · 2026
    Article
  4. Review
  5. Epigenetic Mechanisms of Suicidal Behavior Formation: A Review.Medical journal of the Islamic Republic of Iran · 2026
    Review
  6. Adenosine AFrontiers in pharmacology · 2026
    Article
  7. Article
  8. Article
  9. Bioelectric; Neuromodulation; Epilepsy; DBS; High-frequency stimulation; Low frequency stimulation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  10. Article
  11. Menstrual psychosis with a marked response to carbamazepine.PCN reports : psychiatry and clinical neurosciences · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Silvia PasquiniDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9442-1428
Chiara ContriDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-3936-5923
Stefania MerighiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-0839-6671
Stefania GessiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Pier Andrea BoreaUniversity of Ferrara, 44121 Ferrara, Italy.
Katia VaraniDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-4562-1348
Fabrizio VincenziDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-5027-1699
University of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosine exerts an important role in the modulation of central nervous system (CNS) activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes, adenosine subtly regulates neurotransmission, interfering with the dopaminergic, glutamatergic, noradrenergic, serotoninergic, and endocannabinoid systems. The inhibitory and facilitating actions of adenosine on neurotransmission are mainly mediated by A

Indexed as

AdenosineAnimalsHumansMental DisordersNervous System DiseasesReceptors, Purinergic P1AdenosineReceptors, Purinergic P1adenosineadenosine receptorsmood disordersneurodevelopment disordersneuropsychiatric disordersneurotransmission

Identifiers

PMID35163142
PMCPMC8835915
OpenAlexW4206972629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.