Evidence map›Paper›PMID 35163108›Full record

ArticleInternational journal of molecular sciences2022

Deep Functional Profiling of Wild Animal Microbiomes Reveals Probiotic

Margarita N Baranova, Arsen M Kudzhaev, Yuliana A Mokrushina, Vladislav V Babenko, Maria A Kornienko, Maja V Malakhova, Victor G Yudin, Maria P Rubtsova, Arthur Zalevsky, Olga A Belozerova and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Animal Microbiomes as a Source of Novel Antibiotic-Producing Strains.International journal of molecular sciences · 2023
    Review
  6. Comparative Genomics ofPHAGE (New Rochelle, N.Y.) · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Margarita N BaranovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Arsen M KudzhaevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-8620-6998
Yuliana A MokrushinaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Vladislav V BabenkoFederal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0003-2242-2127
Maria A KornienkoFederal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-1966-8452
Maja V MalakhovaFederal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Victor G YudinFederal Scientific Center of the East Asia Terrestrial Biodiversity, Far-Eastern Branch of Russian Academy of Science, 690022 Vladivostok, Russia.
Maria P RubtsovaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Arthur ZalevskyShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-6987-8119
Olga A BelozerovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-5603-5371
Sergey KovalchukShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Yuriy N ZhuravlevFederal Scientific Center of the East Asia Terrestrial Biodiversity, Far-Eastern Branch of Russian Academy of Science, 690022 Vladivostok, Russia.
Elena N IlinaFederal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Alexander G GabibovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Ivan V SmirnovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-0384-6568
Stanislav S TerekhovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0003-2220-0452
Institute of Bioorganic Chemistry · RULomonosov Moscow State University · RUFederal Medical-Biological Agency · RUFederal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS · RU

Funding

Ministry of Science and Higher Education of the Russian Federation №075-15-2021-1049
6 · The paper itself

Abstract

The biodiversity of microorganisms is maintained by intricate nets of interactions between competing species. Impaired functionality of human microbiomes correlates with their reduced biodiversity originating from aseptic environmental conditions and antibiotic use. Microbiomes of wild animals are free of these selective pressures. Microbiota provides a protecting shield from invasion by pathogens in the wild, outcompeting their growth in specific ecological niches. We applied ultrahigh-throughput microfluidic technologies for functional profiling of microbiomes of wild animals, including the skin beetle, Siberian lynx, common raccoon dog, and East Siberian brown bear. Single-cell screening of the most efficient killers of the common human pathogen

Indexed as

MicrobiotaAnimalsAnimals, WildAnti-Bacterial AgentsBacillus pumilusBacterial ProteinsEscherichia coliGenome, BacterialMetabolomeMultigene FamilyProbioticsStaphylococcus aureusAnti-Bacterial AgentsBacterial Proteinsamicoumacinbiodiversitybiosynthetic gene clusters (BGCs)droplet microfluidicsmetabolomic fingerprintingprobiotic discoveryultrahigh-throughput screeningwild animal microbiomes

Identifiers

PMID35163108
PMCPMC8835302
OpenAlexW4206386022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.