Evidence map›Paper›PMID 35163050›Full record

ArticleInternational journal of molecular sciences2022

Cysteine 467 of the ASCT2 Amino Acid Transporter Is a Molecular Determinant of the Antiport Mechanism.

Mariafrancesca Scalise, Gilda Pappacoda, Tiziano Mazza, Lara Console, Lorena Pochini, Cesare Indiveri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. [Glutamine metabolic reprogramming in regulating the occurrence and development of osteosarcoma].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  3. Targeting glutamine metabolism as a potential target for cancer treatment.Journal of experimental & clinical cancer research : CR · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mariafrancesca ScaliseUnit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze Della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata of Rende, Italy.ORCID 0000-0003-3860-6844
Gilda PappacodaUnit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze Della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata of Rende, Italy.
Tiziano MazzaUnit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze Della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata of Rende, Italy.
Lara ConsoleUnit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze Della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata of Rende, Italy.ORCID 0000-0002-0238-0946
Lorena PochiniUnit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze Della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata of Rende, Italy.
Cesare IndiveriUnit of Biochemistry and Molecular Biotechnology, Department DiBEST (Biologia, Ecologia, Scienze Della Terra), University of Calabria, Via P. Bucci 4C, 87036 Arcavacata of Rende, Italy.ORCID 0000-0001-9818-6621
University of Calabria · ITInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies · IT

Funding

Ministry of Education, Universities and Research 2017PAB8EMMinistry of Education, Universities and Research STAR_2, CIR01_00008_478213
6 · The paper itself

Abstract

The plasma membrane transporter ASCT2 is a well-known Na

Indexed as

Amino Acid SubstitutionAmino Acid Transport System ASCBinding SitesCloning, MolecularCysteineGlutamineHumansIon TransportMinor Histocompatibility AntigensModels, MolecularMutagenesis, Site-DirectedProtein ConformationSaccharomycetalesAmino Acid Transport System ASCCysteineGlutamineMinor Histocompatibility AntigensSLC1A5 protein, human3D structuresamino acidglutamineliposomeover-expressionsite-directed mutanttransport

Identifiers

PMID35163050
PMCPMC8835248
OpenAlexW4205182846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.