Evidence map›Paper›PMID 35163046›Full record

ArticleInternational journal of molecular sciences2022

Roux-En-Y Gastric Bypass (RYGB) Surgery during High Liquid Sucrose Diet Leads to Gut Microbiota-Related Systematic Alterations.

Laimdota Zizmare, Christina N Boyle, Sabrina Buss, Sandrine Louis, Laura Kuebler, Ketki Mulay, Ralf Krüger, Lara Steinhauer, Isabelle Mack, Manuel Rodriguez Gomez and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Laimdota ZizmareWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Eberhard Karls University of Tübingen, Röntgenweg 13, 72076 Tübingen, Germany.ORCID 0000-0001-7208-3659
Christina N BoyleInstitute of Veterinary Physiology, University of Zurich, Winterthurerstraße 260, CH-8057 Zurich, Switzerland.
Sabrina BussWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Eberhard Karls University of Tübingen, Röntgenweg 13, 72076 Tübingen, Germany.
Sandrine LouisDepartment of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Haid-und-Neu-Straße 9, 76131 Karlsruhe, Germany.
Laura KueblerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Eberhard Karls University of Tübingen, Röntgenweg 13, 72076 Tübingen, Germany.
Ketki MulayDepartment of Medical Psychology and Behavioral Neurobiology, Eberhard Karls University of Tübingen, Silcherstraße 5, 72076 Tübingen, Germany.
Ralf KrügerDepartment of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Haid-und-Neu-Straße 9, 76131 Karlsruhe, Germany.ORCID 0000-0003-1904-8621
Lara SteinhauerDepartment of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Haid-und-Neu-Straße 9, 76131 Karlsruhe, Germany.
Isabelle MackDepartment of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Osianderstraße 5, 72076 Tübingen, Germany.
Manuel Rodriguez GomezDepartment of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Haid-und-Neu-Straße 9, 76131 Karlsruhe, Germany.
Kristina HerfertWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Eberhard Karls University of Tübingen, Röntgenweg 13, 72076 Tübingen, Germany.
Yvonne RitzeDepartment of Medical Psychology and Behavioral Neurobiology, Eberhard Karls University of Tübingen, Silcherstraße 5, 72076 Tübingen, Germany.
Christoph TrautweinWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Eberhard Karls University of Tübingen, Röntgenweg 13, 72076 Tübingen, Germany.
Siemens (Germany) · DEMax Rubner Institut · DEUniversity of Tübingen · DEUniversitätsklinikum Tübingen · DEUniversity of Zurich · CH

Funding

DFG RI 2360/2-1
6 · The paper itself

Abstract

Roux-en-Y gastric bypass (RYGB) surgery has been proven successful in weight loss and improvement of co-morbidities associated with obesity. Chronic complications such as malabsorption of micronutrients in up to 50% of patients underline the need for additional therapeutic approaches. We investigated systemic RYGB surgery effects in a liquid sucrose diet-induced rat obesity model. After consuming a diet supplemented with high liquid sucrose for eight weeks, rats underwent RYGB or control sham surgery. RYGB, sham pair-fed, and sham ad libitum-fed groups further continued on the diet after recovery. Notable alterations were revealed in microbiota composition, inflammatory markers, feces, liver, and plasma metabolites, as well as in brain neuronal activity post-surgery. Higher fecal 4-aminobutyrate (GABA) correlated with higher Bacteroidota and

Indexed as

AnimalsBacteriaCaloric RestrictionCase-Control StudiesC-Reactive ProteinDisease Models, AnimalDNA, BacterialDNA, RibosomalFecesGastric BypassGastrointestinal MicrobiomeGlucoseMaleMetabolomicsObesityPhylogenyC-Reactive ProteinDNA, BacterialDNA, RibosomalGlucoseRNA, Ribosomal, 16SSucrose3-hydroxybutyrateGABAgut-brain axisinflammationmetabolomicsmicrobiomeRYGB

Identifiers

PMID35163046
PMCPMC8835548
OpenAlexW4206679048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.