Evidence map›Paper›PMID 35162987›Full record

ArticleInternational journal of molecular sciences2022

Analogs of the Heat Shock Protein 70 Inhibitor MKT-077 Suppress Medullary Thyroid Carcinoma Cells.

Seung-Keun Hong, Dmytro Starenki, Oleta T Johnson, Jason E Gestwicki, Jong-In Park

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Recent Advances in Thyroid Cancer Research.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Seung-Keun HongDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-5686-7541
Dmytro StarenkiDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Oleta T JohnsonDepartment of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA.
Jason E GestwickiDepartment of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA.
Jong-In ParkDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-7248-4735
Medical College of Wisconsin · USUniversity of California, San Francisco · US

Funding

Molecular Chaperones and Small MoleculesR01NS059690 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jason E Gestwicki · 2008 to 2026
$7.9M
Mechanisms of MEK/ERK growth arrest signalingR01CA138441 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI PARK, JONG-IN · 2010 to 2020
$2.9M
NCI NIH HHS R01 CA138441NIH HHS CA138441NIH HHS NS059690NINDS NIH HHS R01 NS059690
6 · The paper itself

Abstract

Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor mainly caused by mutations in the

Indexed as

Carcinoma, NeuroendocrineThyroid NeoplasmsAnimalsCell Line, TumorHSP70 Heat-Shock ProteinsHumansMicePyridinesThiazolesHSP70 Heat-Shock ProteinsMKT 077PyridinesThiazolesHSPA9JG-98medullary thyroid carcinomamitochondriaMKT-077mortalin

Identifiers

PMID35162987
PMCPMC8835675
OpenAlexW4206379853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.