Evidence map›Paper›PMID 35162975›Full record

ArticleInternational journal of molecular sciences2022

Functional Characterization of an In-Frame Deletion in the Basic Domain of the Retinal Transcription Factor ATOH7.

David Atac, Lucas Mohn, Silke Feil, Kevin Maggi, Dominik Haenni, Britta Seebauer, Samuel Koller, Wolfgang Berger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Inherited Retinal Diseases.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

David AtacInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.ORCID 0000-0001-6537-8627
Lucas MohnInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.ORCID 0000-0001-9449-2189
Silke FeilInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.
Kevin MaggiInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.ORCID 0000-0002-1333-7070
Dominik HaenniCenter for Microscopy and Image Analysis, University of Zurich, 8057 Zurich, Switzerland.
Britta SeebauerInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.
Samuel KollerInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.ORCID 0000-0003-0965-0539
Wolfgang BergerInstitute of Medical Molecular Genetics, University of Zurich, 8952 Schlieren, Switzerland.ORCID 0000-0002-0370-3815
University of Zurich · CH

Funding

SCHWEIZERISCHER NATIONALFONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG 31003A_122359VELUX FOUNDATION 1371
6 · The paper itself

Abstract

Basic helix-loop-helix (bHLH) transcription factors are evolutionarily conserved and structurally similar proteins important in development. The temporospatial expression of atonal bHLH transcription factor 7 (

Indexed as

Basic Helix-Loop-Helix ProteinsNerve Tissue ProteinsDNAHEK293 CellsHumansMutant ProteinsATOH7 protein, humanBasic Helix-Loop-Helix ProteinsDNAMutant ProteinsNerve Tissue Proteinsatonal bHLH transcription factor 7 (ATOH7)basic helix–loop–helix (bHLH)cycloheximide (CHX) chase assaydimerization-mediated proteasomal degradationDNA-bindingfluorescence lifetime imaging-Förster resonance energy transfer (FLIM–FRET)nonsyndromic congenital retinal nonattachment (NCRNA)protein dimerizationretinasynergistic nuclear import

Identifiers

PMID35162975
PMCPMC8834682
OpenAlexW4206507593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.