Evidence map›Paper›PMID 35162966›Full record

ReviewInternational journal of molecular sciences2022

Impairment of Anti-Aggregatory Responses to Nitric Oxide and Prostacyclin: Mechanisms and Clinical Implications in Cardiovascular Disease.

Yuliy Y Chirkov, Thanh H Nguyen, John D Horowitz

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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  8. The essential oil from the rhizomes ofFrontiers in pharmacology · 2025
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  17. A Novel Polysaccharide fromMolecules (Basel, Switzerland) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yuliy Y ChirkovCardiology Laboratory, Basil Hetzel Institute, The Queen Elizabeth Hospital, The University of Adelaide, Adelaide 5011, Australia.
Thanh H NguyenCardiology Laboratory, Basil Hetzel Institute, The Queen Elizabeth Hospital, The University of Adelaide, Adelaide 5011, Australia.
John D HorowitzCardiology Laboratory, Basil Hetzel Institute, The Queen Elizabeth Hospital, The University of Adelaide, Adelaide 5011, Australia.
Queen Elizabeth Hospital · AUBasil Hetzel Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The propensity towards platelet-rich thrombus formation increases substantially during normal ageing, and this trend is mediated by decreases in platelet responsiveness to the anti-aggregatory nitric oxide (NO) and prostacyclin (PGI

Indexed as

Adenylyl CyclasesCardiovascular DiseasesDrug ResistanceEpoprostenolHumansNitric OxideOxidative StressSignal TransductionSoluble Guanylyl CyclaseThromboembolismAdenylyl CyclasesEpoprostenolNitric OxideSoluble Guanylyl Cyclaseadenylate cyclasecardiovascular diseasesnitric oxideoxidative stressplateletsprostacyclinsoluble guanylate cyclase

Identifiers

PMID35162966
PMCPMC8835624
OpenAlexW4206715488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.