Evidence map›Paper›PMID 35162963›Full record

ArticleInternational journal of molecular sciences2022

Osteopontin on the Dental Implant Surface Promotes Direct Osteogenesis in Osseointegration.

Sanako Makishi, Tomohiko Yamazaki, Hayato Ohshima

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Osteopontin de-escalates the foreign body response.Nature biomedical engineering · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sanako MakishiDivision of Anatomy and Cell Biology of the Hard Tissue, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.
Tomohiko YamazakiResearch Center for Functional Materials, National Institute for Materials Science, Tsukuba 305-0047, Japan.ORCID 0000-0003-2136-8042
Hayato OhshimaDivision of Anatomy and Cell Biology of the Hard Tissue, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0000-0001-8571-9900
Niigata University · JPNational Institute for Materials Science · JP

Funding

Japan Society for the Promotion of Science 19J11806
6 · The paper itself

Abstract

After dental implantation, osteopontin (OPN) is deposited on the hydroxyapatite (HA) blasted implant surface followed by direct osteogenesis, which is significantly disturbed in

Indexed as

Acid PhosphataseAnimalsDental ImplantationDental ImplantsDurapatiteGene Knockout TechniquesMiceModels, AnimalOsseointegrationOsteogenesisOsteopontinRecombinant ProteinsAcid PhosphataseDental ImplantsDurapatiteOsteopontinRecombinant ProteinsSpp1 protein, mousedental implantsmaxillamice (knockout)osseointegrationosteopontintitaniumtooth extraction

Identifiers

PMID35162963
PMCPMC8835189
OpenAlexW4206637850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.