Evidence map›Paper›PMID 35162535›Full record

ArticleInternational journal of environmental research and public health2022

Policies and Toxicological Screenings for No Drug Addiction: An Example from the Civil Aviation Workforce.

Michele Treglia, Margherita Pallocci, Giorgio Ricciardi-Tenore, Flavio Baretti, Giovanna Bianco, Paola Castellani, Fabrizio Pizzuti, Valeria Ottaviano, Pierluigi Passalacqua, Claudio Leonardi and 3 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Towards the Validation of an Observational Tool to Detect Impaired Drivers-An Online Video Study.International journal of environmental research and public health · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michele TregliaSection of Legal Medicine, Social Security and Forensic Toxicology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-9434-2604
Margherita PallocciSection of Legal Medicine, Social Security and Forensic Toxicology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-3169-2906
Giorgio Ricciardi-TenoreDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Flavio BarettiDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giovanna BiancoDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Paola CastellaniDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Fabrizio PizzutiDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Valeria OttavianoSection of Legal Medicine, Social Security and Forensic Toxicology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1491-413X
Pierluigi PassalacquaSection of Legal Medicine, Social Security and Forensic Toxicology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Claudio LeonardiSubstance Abuse and Mental Health Services (Ser.D)-Local Health Authority (ASL) RM2, 00133 Rome, Italy.ORCID 0000-0002-9348-5574
Luca CoppetaDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-2470-6107
Agostino MessineoSection of Legal Medicine, Social Security and Forensic Toxicology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Roberta TittarelliSection of Legal Medicine, Social Security and Forensic Toxicology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSince 2008, Italian legislators, with the aim of ensuring public safety, have made it mandatory for an occupational doctor (OD) to assess specific categories of workers to exclude those who may have consumed drugs of abuse. Due to the relevance of work activities relating to the civil aviation and airport sector, a policy based on the use of training and information tools, as well as a health surveillance protocol, has been undertaken since 2009. MATERIALS AND

methodsA total of 61,008 workers at a commercial airline underwent health surveillance between 2009 and 2019. Following ≤24 h notification, their urine was screened for opiates, cocaine, cannabinoids, amphetamines, methamphetamines, and methylenedioxymethamphetamine (MDMA) using an immunochemical test. Positive results were confirmed using Gas Chromatography-Mass Spectrometry (GC/MS) or Liquid Chromatography -Mass Spectrometry (LC/MS). In confirmed cases, the workers were declared unfit and sent to a specialized laboratory for a second level analysis.

resultsPositive results, initially >1%, have halved in the last four years (<0.5%). The percentage of positive results was consistently very low among pilots and, moreover, the rare positive cases detected were due to a cross-reactivity phenomena. The highest and most discontinuous percentages seen occurred in the population undergoing a pre-employment examination. Regarding the types of substance used, a prevalence of cannabis (58.52%) and cocaine (35.2%) use was observed.

conclusionsThe data presented indicate that the air transport sector, in all its components (ground workers and air crews), has a very limited number of substance abusers, and this number tends to decrease over time and with work seniority. Another aspect of particular interest, and which is more specific to toxicology, concerns the detection of cross-reactivity in urinary immunochemical screening between the antibodies to drugs of abuse and certain other drugs, such as anti-inflammatories or antibiotics; as well as foods, and other commonly used substances.

Indexed as

AviationIllicit DrugsSubstance-Related DisordersHumansPolicySubstance Abuse DetectionWorkforceIllicit Drugshealth policyoccupational healthoccupational medicinesubstance abusesubstance-related disorderstoxicology

Identifiers

PMID35162535
PMCPMC8835168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.