Evidence map›Paper›PMID 35162279›Full record

ReviewInternational journal of environmental research and public health2022

Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women's Health.

Jelonia T Rumph, Victoria R Stephens, Joanie L Martin, LaKendria K Brown, Portia L Thomas, Ayorinde Cooley, Kevin G Osteen, Kaylon L Bruner-Tran

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Follicle-Stimulating Hormone Promotes the Development of Endometrial CancerInternational journal of environmental research and public health · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jelonia T RumphDepartment of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.ORCID 0000-0003-2082-6355
Victoria R StephensWomen's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Joanie L MartinDepartment of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
LaKendria K BrownDepartment of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.ORCID 0000-0001-8312-062X
Portia L ThomasDepartment of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.ORCID 0000-0002-1374-5015
Ayorinde CooleyDepartment of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Kevin G OsteenWomen's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Kaylon L Bruner-TranWomen's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Meharry Medical College · USVanderbilt University · US

Funding

TRAINING IN PHARMACOLOGICAL SCIENCEST32GM007628 · NIGMS · VANDERBILT UNIVERSITY · PI BARNETT, JOEY VICTOR, KAVALALI, EGE T · 1985 to 2022
$11.2M
Role of cancer-associated mutations in endometriosisR01HD096147 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SEGARS, JAMES H., SHIH, IE-MING · 2019 to 2023
$3.4M
MOLECULAR PARASITOLOGY TRAINING PROGRAMT32AI007281 · NIAID · MEHARRY MEDICAL COLLEGE · PI NDE, PIUS N · 1985 to 2025
$3.2M
Paternal Toxicant Exposure Impacts Testicular-Placental CrosstalkI01BX002853 · VA · VETERANS HEALTH ADMINISTRATION · PI OSTEEN, KEVIN G · 2016 to 2020
–
BLRD VA I01 BX002853NIAID NIH HHS T32 AI007281NICHD NIH HHS R01 HD096147NIGMS NIH HHS T32 GM007628
6 · The paper itself

Abstract

Over the years, industrial accidents and military actions have led to unintentional, large-scale, high-dose human exposure to environmental contaminants with endocrine-disrupting action. These historical events, in addition to laboratory studies, suggest that exposure to toxicants such as dioxins and polychlorinated biphenyls negatively impact the reproductive system and likely influence the development of gynecologic diseases. Although high-level exposure to a single toxicant is rare, humans living in industrialized countries are continuously exposed to a complex mixture of manmade and naturally produced endocrine disruptors, including persistent organic pollutants and heavy metals. Since minorities are more likely to live in areas with known environmental contamination; herein, we conducted a literature review to identify potential associations between toxicant exposure and racial disparities in women's health. Evidence within the literature suggests that the body burden of environmental contaminants, especially in combination with inherent genetic variations, likely contributes to previously observed racial disparities in women's health conditions such as breast cancer, endometriosis, polycystic ovarian syndrome, uterine fibroids, and premature birth.

Indexed as

DioxinsEndocrine DisruptorsEnvironmental PollutantsPolychlorinated BiphenylsEnvironmental ExposureFemaleHazardous SubstancesHumansPregnancyWomen's HealthDioxinsEndocrine DisruptorsEnvironmental PollutantsHazardous SubstancesPolychlorinated Biphenylsenvironmental contaminantshealth disparitiesminoritiespollutionwomen’s health

Identifiers

PMID35162279
PMCPMC8835285
OpenAlexW4206972574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.