Evidence map›Paper›PMID 35160746›Full record

ArticleMaterials (Basel, Switzerland)2022

Poly-Lysine Dendritic Nanocarrier to Target Epidermal Growth Factor Receptor Overexpressed Breast Cancer for Methotrexate Delivery.

Pratibha Narayanan, Anju Krishnan Anitha, Neethu Ajayakumar, Kesavakurup Santhosh Kumar

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. A DFX-based iron nanochelator for cancer therapy.Frontiers in bioengineering and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pratibha NarayananPathogen Biology Division, Rajiv Gandhi Centre for Biotechnology, Bio-Innovation Centre, KINFRA Park, Chanthavila (PO), Thiruvananthapuram 695585, Kerala, India.
Anju Krishnan AnithaPathogen Biology Division, Rajiv Gandhi Centre for Biotechnology, Bio-Innovation Centre, KINFRA Park, Chanthavila (PO), Thiruvananthapuram 695585, Kerala, India.
Neethu AjayakumarPathogen Biology Division, Rajiv Gandhi Centre for Biotechnology, Bio-Innovation Centre, KINFRA Park, Chanthavila (PO), Thiruvananthapuram 695585, Kerala, India.
Kesavakurup Santhosh KumarPathogen Biology Division, Rajiv Gandhi Centre for Biotechnology, Bio-Innovation Centre, KINFRA Park, Chanthavila (PO), Thiruvananthapuram 695585, Kerala, India.ORCID 0000-0003-1885-2909

Funding

Department of Biotechnology BT/PR9907.NNT/28/65/2007Department of Biotechnology DBT/JRF/BET-16/I/2016/AL/12Kerala State Council for Science, Technology and Environment No.01/FSHP-MAIN/2014/KSCSTE
6 · The paper itself

Abstract

A fourth generation poly-lysine dendritic nanocarrier (P

Indexed as

breast cancerepidermal growth factor receptorin silico approachin vivo evaluationmethotrexatepoly-lysine dendritic nanocarriersolid-phase peptide synthesistargeted drug deliverytetrapeptide spacer

Identifiers

PMID35160746
PMCPMC8836561

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.